Cancer control and functional outcomes after radical prostatectomy as markers of surgical quality: Analysis of heterogeneity between surgeons at a single cancer center Journal Article


Authors: Vickers, A.; Savage, C.; Bianco, F.; Mulhall, J.; Sandhu, J.; Guillonneau, B.; Cronin, A.; Scardino, P.
Article Title: Cancer control and functional outcomes after radical prostatectomy as markers of surgical quality: Analysis of heterogeneity between surgeons at a single cancer center
Abstract: Background: Previous studies have shown that complications and biochemical recurrence rates after radical prostatectomy (RP) vary between different surgeons to a greater extent than might be expected by chance. Data on urinary and erectile outcomes, however, are lacking. Objective: In this study, we examined whether between-surgeon variation, known as heterogeneity, exists for urinary and erectile outcomes after RP. Design, setting, and participants: Our study consisted of 1910 RP patients who were treated by 1 of 11 surgeons between January 1999 and July 2007. Intervention: All patients underwent RP at Memorial Sloan-Kettering Cancer Center. Measurements: Patients were evaluated for functional outcome 1 yr after surgery. Multivariable random effects models were used to evaluate the heterogeneity in erectile or urinary outcome between surgeons, after adjustment for case mix (age, prostate-specific antigen, pathologic stage and grade, comorbidities) and year of surgery. Results and limitations: We found significant heterogeneity in functional outcomes after RP (p < 0.001 for both urinary and erectile function). Four surgeons had adjusted rates of full continence <75%, whereas three had rates >85%. For erectile function, two surgeons in our series had adjusted rates <20%; another two had rates >45%. We found some evidence suggesting that surgeons' erectile and urinary outcomes were correlated. Contrary to the hypothesis that surgeons "trade off" functional outcomes and cancer control, better rates of functional preservation were associated with lower biochemical recurrence rates. Conclusions: A patient's likelihood of recovering erectile and urinary function may differ depending on which of two surgeons performs his RP. Functional preservation does not appear to come at the expense of cancer control; rather, both are related to surgical quality. © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
Keywords: prostate cancer; radical prostatectomy; erectile funcion; surgeon heterogeneity; urinary function
Journal Title: European Urology
Volume: 59
Issue: 3
ISSN: 0302-2838
Publisher: Elsevier Science, Inc.  
Date Published: 2011-03-01
Start Page: 317
End Page: 322
Language: English
DOI: 10.1016/j.eururo.2010.10.045
PROVIDER: scopus
PUBMED: 21095055
PMCID: PMC3060298
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 4 March 2011" - "CODEN: EUURA" - "Source: Scopus"
Altmetric Score
MSK Authors
  1. Jaspreet Sandhu
    99 Sandhu
  2. Caroline Savage
    80 Savage
  3. Peter T Scardino
    621 Scardino
  4. John P Mulhall
    399 Mulhall
  5. Andrew J Vickers
    565 Vickers
  6. Fernando J Bianco
    72 Bianco