Screening for psychologic distress in ambulatory cancer patients: A multicenter evaluation of the distress thermometer Journal Article


Authors: Jacobsen, P. B.; Donovan, K. A.; Trask, P. C.; Fleishman, S. B.; Zabora, J.; Baker, F.; Holland, J. C.
Article Title: Screening for psychologic distress in ambulatory cancer patients: A multicenter evaluation of the distress thermometer
Abstract: BACKGROUND. Based on evidence that psychologic distress often goes unrecognized although it is common among cancer patients, clinical practice guidelines recommend routine screening for distress. For this study, the authors sought to determine whether the single-item Distress Thermometer (DT) compared favorably with longer measures currently used to screen for distress. METHODS. Patients (n = 380) who were recruited from 5 sites completed the DT and identified the presence or absence of 34 problems using a standardized list. Participants also completed the 14-item Hospital Anxiety and Depression Scale (HADS) and an 18-item version of the Brief Symptom Inventory (BSI-18), both of which have established cutoff scores for identifying clinically significant distress. RESULTS. Receiver operating characteristic (ROC) curve analyses of DT scores yielded area under the curve estimates relative to the HADS cutoff score (0.80) and the BSI-18 cutoff scores (0.78) indicative of good overall accuracy. ROC analyses also showed that a DT cutoff score of 4 had optimal sensitivity and specificity relative to both the HADS and BSI-18 cutoff scores. Additional analyses indicated that, compared with patients who had DT scores < 4, patients who had DT scores a 4 were more likely to be women, have a poorer performance status, and report practical, family, emotional, and physical problems (P & 0.05). CONCLUSIONS. Findings confirm that the single-item DT compares favorably with longer measures used to screen for distress. A DT cutoff score of 4 yielded optimal sensitivity and specificity in a general cancer population relative to established cutoff scores on longer measures. The use of this cutoff score identified patients with a range of problems that were likely to reflect psychologic distress. © 2005 American Cancer Society.
Keywords: adult; aged; middle aged; major clinical study; cancer patient; sensitivity and specificity; neoplasms; prevalence; depression; screening; psychiatric status rating scales; scoring system; ambulatory care; distress syndrome; mental disease; brief symptom inventory; rating scale; anxiety; symptomatology; screening test; roc curve; stress, psychological; psychometrics; receiver operating characteristic; hospital anxiety and depression scale; personality inventory; distress thermometer; psychologic distress
Journal Title: Cancer
Volume: 103
Issue: 7
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 2005-04-01
Start Page: 1494
End Page: 1502
Language: English
DOI: 10.1002/cncr.20940
PUBMED: 15726544
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 200" - "Export Date: 24 October 2012" - "CODEN: CANCA" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Jimmie C B Holland
    380 Holland