Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results Journal Article
| Authors: | Hsiung, C. Y.; Hunt, M. A.; Yorke, E. D.; Chui, C. S.; Hu, J.; Xiong, J. P.; Ling, C. C.; Lo, S. K.; Wang, C. J.; Huang, E. Y.; Amols, H. I. |
| Article Title: | Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results |
| Abstract: | The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry. © 2005 Elsevier Ireland Ltd. All rights reserved. |
| Keywords: | clinical article; controlled study; salvage therapy; treatment planning; cancer radiotherapy; radiation dose; recurrent cancer; dose-response relationship, radiation; intensity-modulated radiotherapy; geometry; carcinoma; radiation injuries; nasopharynx carcinoma; radiotherapy, conformal; dose fractionation; nasopharyngeal carcinoma; nasopharyngeal neoplasms; optimization; frequency modulation; inverse planning; anatomic factor |
| Journal Title: | Radiotherapy and Oncology |
| Volume: | 77 |
| Issue: | 1 |
| ISSN: | 0167-8140 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2005-10-01 |
| Start Page: | 53 |
| End Page: | 57 |
| Language: | English |
| DOI: | 10.1016/j.radonc.2005.04.017 |
| PUBMED: | 16246743 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 24 October 2012" - "CODEN: RAOND" - "Source: Scopus" |
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