Complications in smokers after postmastectomy tissue expander/implant breast reconstruction Journal Article
| Authors: | Goodwin, S. J.; McCarthy, C. M.; Pusic, A. L.; Bui, D.; Howard, M.; Disa, J. J.; Cordeiro, P. G.; Mehrara, B. J.; Leber, D. C.; Lee, W. P. A.; Hazen, A.; Leitner, D. W.; LaManna, J. V. |
| Article Title: | Complications in smokers after postmastectomy tissue expander/implant breast reconstruction |
| Abstract: | Smoking is universally considered to be a risk factor for surgical complications. The incidence of complications following tissue expander/implant breast reconstruction in patients who smoke has not been previously evaluated. A review of complications following tissue expander/implant reconstruction in 515 patients was performed. Patients who had 2-stage. tissue expander/implant reconstruction at Memorial Sloan-Kettering Cancer Center between May 2002 and December 2003 were included. Complications in smokers (n = 132) and nonsmokers (n = 383) were compared. The rate of overall complications, reconstructive failure, mastectomy flap necrosis, and infectious complications was significantly higher in smokers compared with nonsmokers. The rate of complications in ex-smokers was also higher than in nonsmokers. Using multivariate statistical analysis to adjust for confounding variables, smoking was identified as independent predictor of postoperative complications. A significant association between smoking status and postoperative complications exists. Thus, smokers who undergo postmastectomy expander/implant reconstruction should be informed of the increased risk of surgical complications and should be counseled on smoking cessation. Copyright © 2005 by Lippincott Williams & Wilkins. |
| Keywords: | adult; controlled study; middle aged; major clinical study; review; cigarette smoking; surgical flaps; cancer staging; prospective studies; mastectomy; logistic models; incidence; risk factors; smoking cessation; smoking; breast neoplasms; breast reconstruction; mammaplasty; necrosis; tissue expansion; postoperative complication; postoperative complications; statistical analysis; complications; chi-square distribution; breast endoprosthesis; breast implants; mastitis; breast necrosis; tissue expander; implants; surgical error |
| Journal Title: | Annals of Plastic Surgery |
| Volume: | 55 |
| Issue: | 1 |
| ISSN: | 0148-7043 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2005-07-01 |
| Start Page: | 16 |
| End Page: | 20 |
| Language: | English |
| DOI: | 10.1097/01.sap.0000168282.81348.b3 |
| PUBMED: | 15985785 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 31" - "Export Date: 24 October 2012" - "CODEN: APCSD" - "Source: Scopus" |
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