Occult primary cancer: Clinical practice guidelines Journal Article


Authors: Ettinger, D. S.; Arnoletti, J. P.; Gockerman, J. P.; Handorf, C.; Havlin, K. A.; Jacobs, C. D.; Javle, M.; Kvols, L.; Lenzi, R.; Rashid, A.; Rhoades, C. A.; Ridge, J. A.; Saltz, L.; Shulman, L. N.; Sondak, V. K.; Thompson, J. A.; Twardowski, P.; Zhen, W.
Article Title: Occult primary cancer: Clinical practice guidelines
Abstract: Occult primary tumors, or cancers of unknown primary site, account for 5% to 10% of all diagnosed cancers. These tumors are manifested by a wide variety of clinical presentations, and for most patients, the disease is incurable. Multiple sites of involvement are shown in more than 50% of patients with occult primary tumors. Common sites of involvement are the liver, lungs, bones, and lymph nodes. Life expectancy is very short, with a median survival of about 6 to 9 months. Given the uncertainties and the generally poor prognosis, patients frequently experience significant psychosocial distress, and empathetic discussion about the natural history of these types of cancers and their prognosis is required. Patient and family education, support, and counseling by the primary oncology team and referral to specialized psychosocial services may help to alleviate this distress. © Journal of the National Comprehensive Cancer Network.
Keywords: cancer chemotherapy; cancer surgery; clinical feature; histopathology; review; cisplatin; fluorouracil; gemcitabine; paclitaxel; cancer radiotherapy; chemotherapy; follow up; carboplatin; metastasis; etoposide; nccn clinical practice guidelines; practice guideline; tumor biopsy; diagnosis; carcinoma; platinum derivative; cancer epidemiology; radiodiagnosis; neoplasms, unknown primary; occult cancer; occult primary disease
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 3
Issue: 2
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2005-03-01
Start Page: 214
End Page: 233
Language: English
PUBMED: 19817031
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 24 October 2012" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Leonard B Saltz
    790 Saltz