Promoting physical activity in childhood cancer survivors Journal Article


Authors: Cox, C. L.; Montgomery, M.; Oeffinger, K. C.; Leisenring, W.; Zeltzer, L.; Whitton, J. A.; Mertens, A. C.; Hudson, M. M.; Robison, L. L.
Article Title: Promoting physical activity in childhood cancer survivors
Abstract: BACKGROUND: Although physical activity may modify the late effects of childhood cancer treatment, from 20% to 52% of adult survivors are sedentary. The authors of this report sought to identify modifiable factors that influence survivors' participation in physical activity. METHODS: Structural equation modeling of data were derived from the Childhood Cancer Survivors Study of adult survivors (current mean age, 30.98 years; mean years since diagnosis, 23.74; mean age at diagnosis, 9.25 years) who were diagnosed between 1970 and 1986. RESULTS: Approximately 40% of the variance in male survivors' recent participation versus nonparticipation in physical activity was explained directly and/or indirectly by self-reported health fears (P = .01), perceived primary-care physician (PCP) expertise (P = .01), baseline exercise frequency (P≤.001), education level (P = .01), self-reported stamina (P = .01), cancer-related pain (P≤.001), fatigue (P≤.001), age at diagnosis (P=.01), cancer-related anxiety (P≤.001), motivation (P = .01), affect (P=.01), and discussion of subsequent cancer risk with the PCP (P≤.001) (N = 256; chi-square test statistic = 53.38; degrees of freedom [df] = 51; P = .38, Comparative Fit Index [CFI] = 1.000; Tucker Lewis Index [TLI] = 1.000; root mean square of approximation [RMSEA] = 0.014; weighted root mean square residual [WRMR] = 0.76). Thirty-one percent of the variance in women' recent physical activity participation was explained directly and/or indirectly by self-reported stamina (P≤ .001), fatigue (P=.01), baseline exercise frequency (P=.01), cancer-related pain (P≤ .001), cancer-related anxiety (P=.01), recency of visits with PCP (<0.001), quality of interaction with the PCP (P=.01), and motivation (P≤.001; N = 366; chi-square test statistic = 67.52; df = 55; P = .12; CFI = 0.98; TLI = 0.98; RMSEA = 0.025; WRMR = 0.76). CONCLUSIONS: Gender-tailored intervention strategies in which providers specifically target motivation, fear, and affect may support physical activity in childhood cancer survivors. © 2008 American Cancer Society.
Keywords: adult; major clinical study; fatigue; neoplasms; models, biological; health behavior; motivation; cancer pain; childhood cancer; age; cancer survivor; survivors; affect; statistical analysis; education; anxiety; physical activity; motor activity; childhood cancer survivors; intervention strategies; sedentary lifestyle; chi square test; comparative fit index; root mean square of approximation; tucker lewis index; weighted root mean square residual; fear; sex factors
Journal Title: Cancer
Volume: 115
Issue: 3
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 2009-02-01
Start Page: 642
End Page: 654
Language: English
DOI: 10.1002/cncr.24043
PUBMED: 19117349
PROVIDER: scopus
PMCID: PMC2653221
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 30 November 2010" - "CODEN: CANCA" - "Source: Scopus"
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  1. Kevin Oeffinger
    296 Oeffinger