Late relapse of testicular germ cell tumors Journal Article

  


Authors: Carver, B. S.; Motzer, R. J.; Kondagunta, G. V.; Sogani, P.; Sheinfeld, J.
Article Title: Late relapse of testicular germ cell tumors
Abstract: The successful multidisciplinary approach for the management of germ cell tumors of the testis has resulted in survival rates of greater than 90% overall. While the majority of relapses in patients with germ cell tumors occur within the first 2 years of treatment, the incidence of late relapse beyond 2 years has been increasing over recent years. The pattern of late relapse suggests that an inadequately controlled retroperitoneum is a major predisposing factor, with up to 80% of late relapses occurring in the retroperitoneum. These tumors tend to be chemorefractory and overall prognosis for patients with late relapse of germ cell tumors is relatively poor, with survival rates of approximately 30% to 40%. In this review, we present the recent data regarding the clinical presentation, patterns of relapse, histologic findings, appropriate treatment options, and outcomes for men with late relapse of germ cell tumors. © 2005 Elsevier Inc. All rights reserved.
Keywords: survival; cancer chemotherapy; treatment outcome; cancer surgery; survival rate; clinical feature; conference paper; antineoplastic agent; neoplasm staging; relapse; recurrence; histology; time factors; testis tumor; testicular neoplasms; testicular cancer; neoplasms, germ cell and embryonal; germ cell tumor; late relapse; rplnd; nsgct
Journal Title: Urologic Oncology: Seminars and Original Investigations
Volume: 23
Issue: 6
ISSN: 1078-1439
Publisher: Elsevier Inc.  
Date Published: 2005-11-01
Start Page: 441
End Page: 445
Language: English
DOI: 10.1016/j.urolonc.2005.06.003
PUBMED: 16301125
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-27844484325&partnerID=40&md5=79810acc71b6c03d15bef35eebf812e1
Notes: --- - "Cited By (since 1996): 15" - "Export Date: 24 October 2012" - "CODEN: UOSOA" - "Source: Scopus"
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MSK Authors
  1. Gnanamba Kondagunta
    46 Kondagunta
  2. Robert Motzer
    1243 Motzer
  3. Joel Sheinfeld
    254 Sheinfeld
  4. Brett Stewart Carver
    143 Carver
  5. Pramod C Sogani
    75 Sogani
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