Soft tissue sarcoma: Advances in understanding and management Journal Article
| Author: | Brennan, M. F. |
| Article Title: | Soft tissue sarcoma: Advances in understanding and management |
| Abstract: | Soft tissue sarcomas are a rare group of neoplasms readily dispersed throughout the body with different histopathologies and different outcomes. The present review summarizes advances made in biology, distribution and natural history, and emphasises predictive models for outcome. Complete resection remains the major factor in providing cure, with limited benefits in the control of the local disease by radiation therapy and only minimal benefit of systemic therapy for metastatic disease. Identification of targeted therapy utilising direct specific molecular targets raises hope that future progress in control, if not cure, is realistic. © 2005 Surgeon. |
| Keywords: | adolescent; adult; cancer survival; aged; surgical technique; survival rate; clinical trial; histopathology; review; cancer recurrence; doxorubicin; chemotherapy, adjuvant; radiotherapy, adjuvant; recurrence risk; cancer grading; diagnostic accuracy; imatinib; genetic predisposition to disease; pyrimidines; ifosfamide; sarcoma; postoperative complication; chromosome aberration; lung metastasis; soft tissue sarcoma; age distribution; piperazines; cancer classification; leiomyosarcoma; malignant fibrous histiocytoma; genetic predisposition; liposarcoma; population distribution; body distribution |
| Journal Title: | Surgeon |
| Volume: | 3 |
| Issue: | 3 |
| ISSN: | 1479-666X |
| Publisher: | Surgeon |
| Date Published: | 2005-06-01 |
| Start Page: | 216 |
| End Page: | 223 |
| Language: | English |
| PUBMED: | 16076008 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 9" - "Export Date: 24 October 2012" - "CODEN: SURGB" - "Source: Scopus" |
