New therapeutics in spine metastases Journal Article
| Author: | Bilsky, M. H. |
| Article Title: | New therapeutics in spine metastases |
| Abstract: | The number of patients who will develop metastatic spinal tumors is estimated to be between 5 and 10% of all cancer patients. As the therapy for systemic cancer improves, the number of patients developing symptomatic spinal tumors that require local therapy will increase. Over the last 10 years there has been a dramatic evolution in our ability to treat spinal tumors. These advances have not only been created by improvements in surgical techniques and instrumentation, but also developments in radiographic imaging, radiation therapy and chemotherapy. It is important for spine surgeons, radiologists, and radiation and medical oncologists to continue developing techniques for spinal salvage that will improve pain relief, achieve mechanical stability, improve or maintain neurologic function and sustain local tumor control. The evolution of these technologies will help to provide palliation and improve quality of life for patients with metastatic disease. © 2005 Future Drugs Ltd. |
| Keywords: | cancer chemotherapy; treatment outcome; bone neoplasms; cancer surgery; osteosynthesis; surgical technique; clinical trial; review; intensity modulated radiation therapy; salvage therapy; cisplatin; cancer combination chemotherapy; cancer adjuvant therapy; cancer radiotherapy; chemotherapy; nuclear magnetic resonance imaging; positron emission tomography; cancer diagnosis; quality control; computer assisted tomography; radiation; etoposide; bisphosphonic acid derivative; diagnostic imaging; oncology; medical instrumentation; radiosurgery; spinal neoplasms; fluorodeoxyglucose f 18; comorbidity; neoplasm metastasis; surgery; cancer control; nerve function; analgesia; radiodiagnosis; polymer; zoledronic acid; spine metastasis; neurology; spine surgery; pamidronic acid; metastatic spine tumor; expert testimony; ketone derivative; poly(methyl methacrylate); bone screw; spine metastases; carbon fiber |
| Journal Title: | Expert Review of Neurotherapeutics |
| Volume: | 5 |
| Issue: | 6 |
| ISSN: | 1473-7175 |
| Publisher: | Informa Healthcare |
| Date Published: | 2005-11-01 |
| Start Page: | 831 |
| End Page: | 840 |
| Language: | English |
| DOI: | 10.1586/14737175.5.6.831 |
| PUBMED: | 16274340 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 15" - "Export Date: 24 October 2012" - "CODEN: ERNXA" - "Source: Scopus" |
