Predictors of intensive care unit admission and related outcome for patients after pancreaticoduodenectomy Journal Article
| Authors: | Bentrem, D. J.; Yeh, J. J.; Brennan, M. F.; Kiran, R.; Pastores, S. M.; Halpern, N. A.; Jaques, D. P.; Fong, Y. |
| Article Title: | Predictors of intensive care unit admission and related outcome for patients after pancreaticoduodenectomy |
| Abstract: | High-volume centers have low morbidity and mortality after pancreaticoduodenectomy (PD). Less is known about treatment pathways and their influence on intensive care unit (ICU) utilization. Patients who underwent PD at a tertiary cancer center during the five-year period between January 1998 and December 2003 were identified from a prospective database. Preoperative and intraoperative factors relating to ICU admission and outcome were analyzed. Five hundred ninety-one pancreaticoduodenectomies were performed during the study period. Of these, 536 patients had complete records for analysis. Of the 536 patients, 51 (10%) were admitted to the ICU after surgery. Admission to the ICU was associated with decreased overall survival (P < .0001). Of the preoperative predictors of ICU admission, serum creatinine, albumin, and increased body mass index (BMI) were associated with ICU admission (P = .02, .05, and .002, respectively). Age, blood glucose, diagnosis of diabetes mellitus, and chronic obstructive pulmonary disease were not predictive of ICU admission on univariate analysis. Of the intraoperative factors, longer operative time and estimated blood loss (EBL) correlated with ICU admission (P = .003 and .0001, respectively). On multivariate analysis, only preoperative BMI and intraoperative EBL were independent predictors of ICU admission (P = .03 and .003, respectively). Patients with a preoperative BMI greater than 30 had a substantially higher risk of ICU admission (relative risk 2.4). The majority of patients who undergo PD do not require admission to the ICU. Factors most associated with ICU admission after PD are increased preoperative BMI and intraoperative blood loss. © 2005 The Society for Surgery of the Alimentary Tract. |
| Keywords: | adult; aged; aged, 80 and over; middle aged; conference paper; pancreatic neoplasms; pancreaticoduodenectomy; statistics; risk factors; risk factor; postoperative complication; postoperative complications; intensive care unit; intensive care units; pancreas tumor; hospital admission; patient admission; perioperative; pancreas neoplasm |
| Journal Title: | Journal of Gastrointestinal Surgery |
| Volume: | 9 |
| Issue: | 9 |
| ISSN: | 1091-255X |
| Publisher: | Springer |
| Date Published: | 2005-12-01 |
| Start Page: | 1307 |
| End Page: | 1312 |
| Language: | English |
| DOI: | 10.1016/j.gassur.2005.09.010 |
| PUBMED: | 16332487 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 25" - "Export Date: 24 October 2012" - "Source: Scopus" |
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