A measure of health-related quality of life among patients with localized prostate cancer: Results from ongoing scale development Journal Article
| Authors: | Befort, C. A.; Zelefsky, M. J.; Scardino, P. T.; Borrayo, E.; Giesler, R. B.; Kattan, M. W. |
| Article Title: | A measure of health-related quality of life among patients with localized prostate cancer: Results from ongoing scale development |
| Abstract: | Background: We revised our prostate cancer-specific measure to better address the physiologic complications of the 3 major therapies for clinically localized prostate cancer and to assess the impact of symptoms on broader aspects of patient functioning. The study used a cross-sectional design, and participants completed the measure in a clinical setting. Patients and Methods: Participants underwent radical prostatectomy (n = 130), external beam radiation therapy (n = 120), or brachytherapy (n = 129). Their mean age was 66 years (standard deviation [SD], 8.2 years), and the median time since treatment was 12.36 months (mean, 21.7; SD, 25.4). Items were derived from previously validated instruments or developed based on the clinical experience of a multidisciplinary group of health professionals. Results: The revised instrument included 46 items that formed 8 physiologic scales (2 urinary, 3 sexual, and 3 bowel function); 3 associated bother scales; and cancer worry, treatment regret, and treatment satisfaction scales. Correlations among scales provided evidence of convergent/divergent validity. Significant group differences were found using analysis of covariance (with time since treatment and age as covariates) on 6 of the 8 physiologic scales and on bowel bother and treatment satisfaction. Conclusion: The instrument provides a sensitive measure of physiologic differences across the 3 primary treatment groups and indicates that there are few differences across treatment groups on broader aspects of health-related quality of life. Further development of the measure is recommended. |
| Keywords: | adult; aged; middle aged; patient satisfaction; major clinical study; cancer radiotherapy; quality of life; prevalence; questionnaires; prostate cancer; prostatic neoplasms; correlation analysis; health status; statistical analysis; prostatectomy; scoring system; brachytherapy; surgery; radiation therapy; intestine function; patient attitude; sexual function; psychometry; treatment satisfaction; urinary tract function; instrument validation; psychosocial measurement; bother scale; cancer worry scale; multivariate analysis of covariance; treatment regret |
| Journal Title: | Clinical Prostate Cancer |
| Volume: | 4 |
| Issue: | 2 |
| ISSN: | 1540-0352 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2005-09-01 |
| Start Page: | 100 |
| End Page: | 108 |
| Language: | English |
| PUBMED: | 16197610 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 24 October 2012" - "CODEN: CPCLC" - "Source: Scopus" |
Citation Impact
Related MSK Work