FDG-PET scanning for detection and staging of extranodal marginal zone lymphomas of the MALT type: A report of 42 cases Journal Article
| Authors: | Beal, K. P.; Yeung, H. W.; Yahalom, J. |
| Article Title: | FDG-PET scanning for detection and staging of extranodal marginal zone lymphomas of the MALT type: A report of 42 cases |
| Abstract: | Background: Although reports have suggested that FDG-PET scans were not useful for staging of extranodal marginal zone lymphomas (MZL), experience at our center suggests otherwise. Thus we reviewed the findings of FDG-PET scans in patients with extranodal MZL seen at our center. Patients and methods: A database of 175 patients with histologically-confirmed diagnoses of extranodal MZL was reviewed. Forty-two patients who had had FDG-PET scans for initial staging were identified. All information was obtained by retrospective review of medical records and PET scans. Results: Thirty-four (81%) patients had focal tracer uptake within verified tumor sites, six (14%) patients did not, and two (5%) patients had indeterminate uptake. Seven of the 34 (21%) patients with uptake within verified tumor sites had uptake in regional lymph nodes and four patients were upstaged due to FDG-PET findings. Eight patients also obtained post-treatment FDG-PET scans. In five of those eight, the repeated FDG-PET scan indicated a complete response, and in three there was an indeterminate or mixed response. Conclusion: FDG-PET scans carried out for initial staging of extranodal MZL detected disease in a high proportion of patients. This study suggests that imaging with FDG-PET scans is useful for both initial staging and follow-up of patients with extranodal MZL. © 2005 European Society for Medical Oncology. |
| Keywords: | adult; clinical article; controlled study; aged; aged, 80 and over; middle aged; retrospective studies; histopathology; cancer patient; cancer staging; positron emission tomography; follow up; cancer diagnosis; neoplasm staging; sensitivity and specificity; radiopharmaceuticals; data base; retrospective study; imaging system; cancer center; medical information; diagnostic value; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; positron-emission tomography; medical record; databases, factual; pet scan; mucosa associated lymphoid tissue lymphoma; lymphoma, mucosa-associated lymphoid tissue; malt lymphoma |
| Journal Title: | Annals of Oncology |
| Volume: | 16 |
| Issue: | 3 |
| ISSN: | 0923-7534 |
| Publisher: | Oxford University Press |
| Date Published: | 2005-03-01 |
| Start Page: | 473 |
| End Page: | 480 |
| Language: | English |
| DOI: | 10.1093/annonc/mdi093 |
| PUBMED: | 15668266 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 62" - "Export Date: 24 October 2012" - "CODEN: ANONE" - "Source: Scopus" |
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