Treatment-related neurotoxicity Journal Article

  


Authors: Abrey, L. E.; Correa, D. D.
Article Title: Treatment-related neurotoxicity
Abstract: Two challenges need to be addressed to improve the outcome of patients with primary central nervous system lymphoma. The first challenge is to develop therapies that result in less toxicity and improved long-term outcome. The second challenge is to develop interventions to help those patients who develop treatment-related neurotoxicity; ongoing collaborative efforts are required to improve communication and understanding of this complication. Long-term follow-up of prospective therapeutic studies should report on both disease control and the development of neurotoxicity. New protocols should include prospective longitudinal measures of neurocognitive function. © 2005 Elsevier Inc. All rights reserved.
Keywords: cancer chemotherapy; clinical trial; review; doxorubicin; side effect; antineoplastic agents; cancer radiotherapy; combined modality therapy; primary central nervous system lymphoma; cytarabine; methotrexate; brain radiation; neuroimaging; neurotoxicity; brain tumor; antineoplastic agent; etoposide; brain injury; gliosis; vincristine; radiation injury; central nervous system neoplasms; vascular fibrosis; atherosclerosis; lymphoma; cognition; mental disease; cognitive defect; seizure; homocysteine; abnormally high substrate concentration in blood; brain ischemia; neurologic disease; white matter; central nervous system disease; nitrosourea derivative; brain atrophy; parkinsonism; retina ischemia; paranoia; neurotoxicity syndromes; pallor; brain spongiosis; nerve cell lesion; periventricular white matter abnormality; white matter abnormality
Journal Title: Hematology/Oncology Clinics of North America
Volume: 19
Issue: 4
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 2005-08-01
Start Page: 729
End Page: 738
Language: English
DOI: 10.1016/j.hoc.2005.05.010
PUBMED: 16083833
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-23244451872&partnerID=40&md5=33b89b1f56d44d3dd21e6cca04c7b17b
Notes: --- - "Cited By (since 1996): 6" - "Export Date: 24 October 2012" - "CODEN: HCNAE" - "Source: Scopus"
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Denise D Correa
    83 Correa
  2. Lauren E Abrey
    278 Abrey
Related MSK Work