Periocular mucosa-associated lymphoid/low grade lymphomas: Treatment with antibiotics Journal Article


Authors: Abramson, D. H.; Rollins, I.; Coleman, M.
Article Title: Periocular mucosa-associated lymphoid/low grade lymphomas: Treatment with antibiotics
Abstract: PURPOSE: To report on the treatment of primary mucosa-associated lymphoid tumors (MALT)/low grade lymphomas of the conjunctiva/orbit treated solely with systemic antibiotics. DESIGN: Retrospective interventional case series. METHODS: Three adult patients with biopsy/marker proven MALT lymphomas of the conjunctiva/orbit were treated with systemic antibiotics and followed for signs of local or systemic relapse. RESULTS: All three patients showed a response to antibiotics based on clinical, ultrasonographic, and MRI/CT imaging studies. Two patients have had complete remissions (42 months follow-up) and one a partial remission (18 months). No systemic relapses have occurred. CONCLUSION: MALT/low grade lymphomas of the conjunctiva/orbit respond to systemic antibiotic therapy and may have complete remissions. © 2005 by Elsevier Inc. All rights reserved.
Keywords: adolescent; adult; human tissue; aged; middle aged; antibiotic agent; antibiotic therapy; retrospective studies; case report; disease marker; nuclear magnetic resonance imaging; magnetic resonance imaging; cancer grading; tumor localization; computer assisted tomography; relapse; tomography, x-ray computed; tumor biopsy; retrospective study; cancer regression; anti-bacterial agents; echography; drug response; lymphoma; remission; doxycycline; orbit tumor; orbital neoplasms; conjunctival neoplasms; mucosa; lymphatic system tumor; conjunctiva tumor; periocular mucosa; lymphoma, mucosa-associated lymphoid tissue
Journal Title: American Journal of Ophthalmology
Volume: 140
Issue: 4
ISSN: 0002-9394
Publisher: Elsevier Science, Inc.  
Date Published: 2005-10-01
Start Page: 729
End Page: 730
Language: English
DOI: 10.1016/j.ajo.2005.03.060
PUBMED: 16226528
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 27" - "Export Date: 24 October 2012" - "CODEN: AJOPA" - "Source: Scopus"
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  1. David H Abramson
    389 Abramson