Ventral hernia following primary laparotomy for ovarian, fallopian tube, and primary peritoneal cancers Journal Article
| Authors: | Long, K. C.; Levinson, K. L.; Diaz, J. P.; Gardner, G. J.; Chi, D. S.; Barakat, R. R.; Leitao, M. M. Jr |
| Article Title: | Ventral hernia following primary laparotomy for ovarian, fallopian tube, and primary peritoneal cancers |
| Abstract: | Objectives: To evaluate the incidence and risk factors for ventral hernia development following primary laparotomy for ovarian, fallopian tube, and peritoneal cancers. Methods: All patients who underwent primary laparotomy for ovarian, tubal, or peritoneal cancer from 3/05 to 12/07 were identified. Hernias were identified radiographically or during physical exam. One-year and 2-year hernia rates were calculated. Clinicopathologic factors were evaluated for an association with the development of hernia using univariate and multivariate analysis. Results: We identified 239 cases with 12 months of follow-up. Median age was 60 years (17-89 years), and median body mass index (BMI) was 25.0 kg/m2 (16.9-58.5 kg/m2). Advanced stage disease (FIGO stage III/IV) was diagnosed in 182/239 (76%). The 1-year hernia rate was 8.8% (21/239): 13/21 (61.9%) were symptomatic, and 8/21 (38.1%) underwent hernia repair operations. On multivariate analysis, only BMI (p = 0.004) and intraperitoneal (IP) chemotherapy (p = 0.016) retained their independent association with hernia development by 12 months. Of the 239 patients, 167 had 24 months of follow-up. The 2-year hernia rate was 23.4% (39/167): 25/39 (64.1%) were symptomatic, and 17/39 (43.6%) underwent hernia repair operations. Multivariate analysis in this group demonstrated that advanced stage (p = 0.033), wound complications (p = 0.029), and BMI (p = 0.012) were independently associated with hernia development by 24 months. Conclusions: The development of ventral hernia is a significant postoperative morbidity in patients undergoing primary surgery for ovarian, tubal, or peritoneal cancer. Independent associations with hernia development include: BMI and IP chemotherapy by Year 1, and BMI, wound complications and advanced stage by Year 2. © 2010 Elsevier Inc. All rights reserved. |
| Keywords: | adolescent; adult; aged; major clinical study; clinical feature; antineoplastic agent; laparotomy; ovarian cancer; disease association; ovary cancer; peritoneum cancer; incidence; risk factor; risk assessment; body mass; evaluation; hernia; wound complication; hernioplasty; calculation; uterine tube tumor; fallopian tube cancer; primary peritoneal cancer; abdominal wall hernia |
| Journal Title: | Gynecologic Oncology |
| Volume: | 120 |
| Issue: | 1 |
| ISSN: | 0090-8258 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2011-01-01 |
| Start Page: | 33 |
| End Page: | 37 |
| Language: | English |
| DOI: | 10.1016/j.ygyno.2010.09.015 |
| PROVIDER: | scopus |
| PUBMED: | 20947151 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 March 2011" - "CODEN: GYNOA" - "Source: Scopus" |
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