Reflectance confocal microscopy in the diagnosis of basal cell carcinoma Journal Article
| Authors: | Gonzalez, S.; Sánchez, V.; Vañ-Galván, S.; Ulrich, M. |
| Article Title: | Reflectance confocal microscopy in the diagnosis of basal cell carcinoma |
| Abstract: | Reflectance confocal microscopy (RCM) is a novel, noninvasive imaging technique based on the collection of in vivo high-resolution images using the differential reflectance of the subcellular structures of the epidermis and dermis when illuminated with a coherent light source. RCM has been used to visualize different skin pathologies, notably actinic keratoses and several types of skin cancer, including squamous and basal cell carcinomas and melanoma. Basal cell carcinoma is particularly amenable to examination by RCM, and its clinical features as visualized by this technique have been described in detail. In addition, RCM allows follow-up of the response of diseased skin to treatment and aids in the determination of the precision of surgical procedures due to the possibility of performing repetitive examinations without further damage of the affected area. © 2011 Expert Reviews Ltd. |
| Keywords: | treatment response; cancer surgery; clinical feature; histopathology; review; cancer recurrence; outcome assessment; recurrence risk; follow up; diagnostic accuracy; phenotype; cell structure; melanoma; reflectance confocal microscopy; imiquimod; basal cell carcinoma; confocal microscopy; sun exposure; differential diagnosis; patient monitoring; in vivo study; diagnostic imaging; radiation exposure; diagnostic value; three dimensional imaging; diagnostic error; intermethod comparison; tumor vascularization; photodynamic therapy; non invasive procedure; chemosurgery; cancer morphology; confocal laser microscopy; cryosurgery; optical coherence tomography; noninvasive diagnosis; skin microscopic diagnosis; solar radiation; skin structure; desiccation; noninvasive management ; refraction index |
| Journal Title: | Expert Review of Dermatology |
| Volume: | 6 |
| Issue: | 1 |
| ISSN: | 1746-9872 |
| Publisher: | Informa Healthcare |
| Date Published: | 2011-02-01 |
| Start Page: | 35 |
| End Page: | 43 |
| Language: | English |
| DOI: | 10.1586/edm.11.1 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 March 2011" - "Source: Scopus" |
