Authors: | LaFemina, J.; Jarnagin, W. R. |
Article Title: | Surgical management of proximal bile duct cancers |
Abstract: | Introduction: Tumors arising from the proximal biliary tree remain particularly challenging with respect to their evaluation and treatment. Complete resection with negative histologic margins is the most effective treatment modality. Results: However, the majority of patients are not candidates for surgery. Summary: Over the last decades, advances have evolved to improve resectability and morbidity after major liver and bile duct resection. However, these disease processes still pose a management challenge. Herein, we provide an overview of proximal bile duct cancers, hilar cholangiocarcinoma (HCCa) and intrahepatic cholangiocarcinoma (ICCa). © 2012 Springer-Verlag. |
Keywords: | treatment outcome; disease-free survival; survival analysis; cancer surgery; disease course; histopathology; review; cancer localization; cisplatin; fluorouracil; advanced cancer; cancer risk; chemoembolization; patient selection; liver neoplasms; gemcitabine; cancer radiotherapy; cancer staging; magnetic resonance imaging; neoplasm staging; preoperative evaluation; cancer palliative therapy; treatment indication; metastasis; differential diagnosis; diagnostic imaging; risk assessment; postoperative complication; liver resection; mitomycin c; neoplasm invasiveness; intrahepatic cholangiocarcinoma; bile duct carcinoma; bile duct neoplasms; cholangiocarcinoma; colon carcinoma; biliary tract surgical procedures; gallbladder cancer; hilar cholangiocarcinoma; bile duct cancer; cholangiography; vater papilla carcinoma |
Journal Title: | Langenbeck's Archives of Surgery |
Volume: | 397 |
Issue: | 6 |
ISSN: | 1435-2443 |
Publisher: | Springer Verlag |
Date Published: | 2012-08-01 |
Start Page: | 869 |
End Page: | 879 |
Language: | English |
DOI: | 10.1007/s00423-012-0928-6 |
PROVIDER: | scopus |
PUBMED: | 22391776 |
DOI/URL: | |
Notes: | --- - "Export Date: 4 September 2012" - "CODEN: LASUF" - "Source: Scopus" |