Surgical management of proximal bile duct cancers Journal Article


Authors: LaFemina, J.; Jarnagin, W. R.
Article Title: Surgical management of proximal bile duct cancers
Abstract: Introduction: Tumors arising from the proximal biliary tree remain particularly challenging with respect to their evaluation and treatment. Complete resection with negative histologic margins is the most effective treatment modality. Results: However, the majority of patients are not candidates for surgery. Summary: Over the last decades, advances have evolved to improve resectability and morbidity after major liver and bile duct resection. However, these disease processes still pose a management challenge. Herein, we provide an overview of proximal bile duct cancers, hilar cholangiocarcinoma (HCCa) and intrahepatic cholangiocarcinoma (ICCa). © 2012 Springer-Verlag.
Keywords: treatment outcome; disease-free survival; survival analysis; cancer surgery; disease course; histopathology; review; cancer localization; cisplatin; fluorouracil; advanced cancer; cancer risk; chemoembolization; patient selection; liver neoplasms; gemcitabine; cancer radiotherapy; cancer staging; magnetic resonance imaging; neoplasm staging; preoperative evaluation; cancer palliative therapy; treatment indication; metastasis; differential diagnosis; diagnostic imaging; risk assessment; postoperative complication; liver resection; mitomycin c; neoplasm invasiveness; intrahepatic cholangiocarcinoma; bile duct carcinoma; bile duct neoplasms; cholangiocarcinoma; colon carcinoma; biliary tract surgical procedures; gallbladder cancer; hilar cholangiocarcinoma; bile duct cancer; cholangiography; vater papilla carcinoma
Journal Title: Langenbeck's Archives of Surgery
Volume: 397
Issue: 6
ISSN: 1435-2443
Publisher: Springer Verlag  
Date Published: 2012-08-01
Start Page: 869
End Page: 879
Language: English
DOI: 10.1007/s00423-012-0928-6
PROVIDER: scopus
PUBMED: 22391776
DOI/URL:
Notes: --- - "Export Date: 4 September 2012" - "CODEN: LASUF" - "Source: Scopus"
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  1. William R Jarnagin
    903 Jarnagin