Prevention of postpneumonectomy syndrome in children with prophylactic tissue expander insertion Journal Article


Authors: Choi, L.; LaQuaglia, M. P.; Cordeiro, P. G.
Article Title: Prevention of postpneumonectomy syndrome in children with prophylactic tissue expander insertion
Abstract: Introduction: Postpneumonectomy syndrome (PPS) is an often life-threatening complication of pneumonectomy that occurs in up to 15% of children. This occurrence is higher than in adults, presumably because of more elastic tissues in younger patients. Methods: We present a case series of 4 pediatric patients at Memorial Sloan Kettering Cancer Center, in whom prophylactic tissue expanders were inserted immediately after pneumonectomy. Results: Insertion of the tissue expander and prevention of PPS was successful in all patients. The presence of the tissue expander did not result in infection in any patient. Our only complication was rupture of the tissue expander in 1 patient, but by the time of removal, a capsule had already formed within the lung and replacement was unnecessary. Conclusion: This case series, although limited in number and follow-up, presents evidence that prophylactic tissue expander insertion appears to be a safe option for children requiring pneumonectomy. Its insertion at the time of pneumonectomy may prevent the devastating complications of PPS. Because it may result in a higher total number of procedures, the benefits must be weighed against the risks of insertion and decisions made for individual patients on a case-by-case basis. © 2012 Elsevier Inc. All rights reserved.
Keywords: child; treatment outcome; child, preschool; implant; mortality; case report; risk benefit analysis; follow up; follow-up studies; computer assisted tomography; lung resection; pneumonectomy; incidence; medical record review; tissue expansion devices; pediatric; sarcoma; postoperative complication; postoperative complications; neuroblastoma; syndrome; prophylaxis; malignant mesothelioma; tissue expander; prosthesis implantation; postpneumonectomy syndrome; myofibroblastic sarcoma; myofibroblastoma; mediastinal diseases
Journal Title: Journal of Pediatric Surgery
Volume: 47
Issue: 7
ISSN: 0022-3468
Publisher: W.B. Saunders Co-Elsevier Inc.  
Date Published: 2012-07-01
Start Page: 1354
End Page: 1357
Language: English
DOI: 10.1016/j.jpedsurg.2012.01.073
PROVIDER: scopus
PUBMED: 22813796
DOI/URL:
Notes: --- - "Export Date: 4 September 2012" - "CODEN: JPDSA" - "Source: Scopus"
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  1. Peter G Cordeiro
    282 Cordeiro