Against quantiles: Categorization of continuous variables in epidemiologic research, and its discontents Journal Article


Authors: Bennette, C.; Vickers, A.
Article Title: Against quantiles: Categorization of continuous variables in epidemiologic research, and its discontents
Abstract: Background: Quantiles are a staple of epidemiologic research: in contemporary epidemiologic practice, continuous variables are typically categorized into tertiles, quartiles and quintiles as a means to illustrate the relationship between a continuous exposure and a binary outcome. Discussion. In this paper we argue that this approach is highly problematic and present several potential alternatives. We also discuss the perceived drawbacks of these newer statistical methods and the possible reasons for their slow adoption by epidemiologists. Summary. The use of quantiles is often inadequate for epidemiologic research with continuous variables. © 2012 Bennette and Vickers; licensee BioMed Central Ltd.
Keywords: patient selection; risk factors; risk factor; models, statistical; sampling studies; epidemiology; bias (epidemiology); statistical model; mass communication; diffusion of innovation; epidemiologic research design
Journal Title: BMC Medical Research Methodology
Volume: 12
ISSN: 1471-2288
Publisher: Biomed Central Ltd  
Date Published: 2012-02-29
Start Page: 21
Language: English
DOI: 10.1186/1471-2288-12-21
PROVIDER: scopus
PMCID: PMC3353173
PUBMED: 22375553
DOI/URL:
Notes: --- - "Export Date: 30 August 2012" - "Source: Scopus"
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  1. Andrew J Vickers
    880 Vickers