Strategies to manage retinoblastoma in developing countries Journal Article
| Authors: | Chantada, G. L.; Qaddoumi, I.; Canturk, S.; Khetan, V.; Ma, Z.; Kimani, K.; Yeniad, B.; Sultan, I.; Sitorus, R. S.; Tacyildiz, N.; Abramson, D. H. |
| Article Title: | Strategies to manage retinoblastoma in developing countries |
| Abstract: | Survival of retinoblastoma is >90% in developed countries but there are significant differences with developing countries in stage at presentation, available treatment options, family compliance, and survival. In low-income countries (LICs), children present with advanced disease, and the reasons are socioeconomic and cultural. In middle-income countries (MICs), survival rates are better (>70%), but there is a high prevalence of microscopically disseminated extraocular disease. Programs for eye preservation have been developed, but toxicity-related mortality is higher. Although effective treatment of microscopically extraocular disease improved the outcome, worldwide survival will be increased only by earlier diagnosis and better treatment adherence. © 2010 Wiley-Liss, Inc. |
| Keywords: | cancer survival; review; cancer incidence; metastasis; prevalence; retinoblastoma; cancer therapy; cancer mortality; patient care; patient compliance; developing countries; developing country; external beam radiotherapy; socioeconomics; late diagnosis; compliance |
| Journal Title: | Pediatric Blood and Cancer |
| Volume: | 56 |
| Issue: | 3 |
| ISSN: | 1545-5009 |
| Publisher: | Wiley Periodicals, Inc |
| Date Published: | 2011-03-01 |
| Start Page: | 341 |
| End Page: | 348 |
| Language: | English |
| DOI: | 10.1002/pbc.22843 |
| PROVIDER: | scopus |
| PUBMED: | 21225909 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 March 2011" - "CODEN: PBCEA" - "Source: Scopus" |
