Authors: | Tempero, M. A.; Arnoletti, J. P.; Behrman, S. W.; Ben-Josef, E.; Benson, A. B. 3rd; Casper, E. S.; Cohen, S. J.; Czito, B.; Ellenhorn, J. D. I.; Hawkins, W. G.; Herman, J.; Hoffman, J. P.; Ko, A.; Komanduri, S.; Koong, A.; Ma, W. W.; Malafa, M. P.; Merchant, N. B.; Mulvihill, S. J.; Muscarella, P. 2nd; Nakakura, E. K.; Obando, J.; Pitman, M. B.; Sasson, A. R.; Tally, A.; Thayer, S. P.; Whiting, S.; Wolff, R. A.; Wolpin, B. M.; Freedman-Cass, D. A.; Shead, D. A. |
Article Title: | Pancreatic adenocarcinoma, version 2.2012 |
Abstract: | The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine pancreas. These NCCN Guidelines Insights provide a summary and explanation of major changes to the 2012 NCCN Guidelines for Pancreatic Adenocarcinoma. The panel made 3 significant updates to the guidelines: 1) more detail was added regarding multiphase CT techniques for diagnosis and staging of pancreatic cancer, and pancreas protocol MRI was added as an emerging alternative to CT; 2) the use of a fluoropyrimidine plus oxaliplatin (e.g., 5-FU/leucovorin/oxaliplatin or capecitabine/oxaliplatin) was added as an acceptable chemotherapy combination for patients with advanced or metastatic disease and good performance status as a category 2B recommendation; and 3) the panel developed new recommendations concerning surgical technique and pathologic analysis and reporting. © JNCCN - Journal of the National Comprehensive Cancer Network. |
Keywords: | cancer surgery; histopathology; review; cancer recurrence; fluorouracil; advanced cancer; cancer combination chemotherapy; capecitabine; pancreas resection; pancreatic neoplasms; cancer staging; nuclear magnetic resonance imaging; cancer diagnosis; neoplasm staging; clinical practice; pancreaticoduodenectomy; adenocarcinoma; metastasis; computer assisted tomography; image analysis; antineoplastic combined chemotherapy protocols; clinical protocol; diagnostic imaging; irinotecan; contrast enhancement; image quality; folinic acid; medical society; pancreas adenocarcinoma; oxaliplatin; fluoropyrimidine |
Journal Title: | Journal of the National Comprehensive Cancer Network |
Volume: | 10 |
Issue: | 6 |
ISSN: | 1540-1405 |
Publisher: | Harborside Press |
Date Published: | 2012-06-01 |
Start Page: | 703 |
End Page: | 713 |
Language: | English |
PROVIDER: | scopus |
PUBMED: | 22679115 |
PMCID: | PMC3807091 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 August 2012" - "Source: Scopus" |