Microcystic adnexal carcinoma of the face treated with radiation therapy: A case report and review of the literature Journal Article


Authors: Pugh, T. J.; Lee, N. Y.; Pacheco, T.; Raben, D.
Article Title: Microcystic adnexal carcinoma of the face treated with radiation therapy: A case report and review of the literature
Abstract: Background. Microcystic adnexal carcinoma is a rare, locally aggressive neoplasm most commonly occurring on the face. Minimal data are available regarding the role of radiation therapy (RT). Methods. Cases treated with RT from 2 comprehensive cancer centers are reviewed along with a review of the literature. Results. Three patients with microcystic adnexal carcinoma of the face were treated with curative intent. One patient received RT as monotherapy. Two patients received postoperative RT (PORT). The patient receiving RT as monotherapy experienced excellent clinical regression, had an in-field recurrence at 48-month follow-up, and is now without evidence of disease after reirradiation. Both patients receiving PORT are without evidence of disease. Conclusion. PORT may improve local control in patients with microcystic adnexal carcinoma, and its use should be considered in patients with high-risk features for local recurrence. RT as monotherapy should be considered when poor cosmetic outcome can be anticipated via standard surgical treatments. © 2011 Wiley Periodicals, Inc.
Keywords: adult; cancer surgery; cancer recurrence; case report; cancer growth; monotherapy; treatment duration; cancer radiotherapy; postoperative care; radiation dose; follow up; ultraviolet radiation; skin cancer; tumor biopsy; hyperkeratosis; cancer invasion; cancer regression; electron therapy; radiation dose fractionation; erythema; brachytherapy; radiation therapy; disease duration; external beam radiotherapy; perineurium; esthetics; chemosurgery; iridium 192; electron; nose cartilage; face injury; repeat procedure; light exposure; cheek; face cancer; microcystic adnexal carcinoma; sclerosing sweat duct carcinoma; chin; lower lip; microcystic adnexal carcinoma of the face; upper lip
Journal Title: Head & Neck
Volume: 34
Issue: 7
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2012-07-01
Start Page: 1045
End Page: 1050
Language: English
DOI: 10.1002/hed.21690
PROVIDER: scopus
PUBMED: 21384456
DOI/URL:
Notes: --- - "Export Date: 1 August 2012" - "CODEN: HEANE" - "Source: Scopus"
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  1. Nancy Y. Lee
    871 Lee