Authors: | Barker, C. A.; Lee, N. Y. |
Article Title: | Radiation therapy for cutaneous melanoma |
Abstract: | Radiation therapy is used infrequently for cutaneous melanoma, despite research suggesting benefit in certain clinical scenarios. This review presents data forming the highest level of evidence supporting the use of radiation therapy. Retrospective and prospective studies demonstrate radiation therapy for primary tumors is associated with high control rates. Two randomized trials have found improvements in regional control with adjuvant radiotherapy to regional lymphatics. Retrospective and prospective studies demonstrate radiation therapy is associated with palliative response and metastatic tumor control. Optimal care of melanoma patients involves radiation therapy; awareness of this is incumbent of clinicians caring for patients with this disease. © 2012 Elsevier Inc. |
Keywords: | drug tolerability; review; bone metastasis; cancer radiotherapy; comparative study; recurrence risk; lymph node metastasis; lymphatic metastasis; evidence-based medicine; melanoma; neoplasm recurrence, local; skin neoplasms; lentigo maligna; malignant lentigo; hutchinson's melanotic freckle; retrospective study; distant metastasis; lymphedema; patient care; brain metastasis; radiation therapy; desmoplastic melanoma; stereotactic radiosurgery; cancer control; skin metastasis; cutaneous melanoma; palliation; high-risk; adjuvant; parotitis; nodal recurrence; malignant lentigo melanoma |
Journal Title: | Dermatologic Clinics |
Volume: | 30 |
Issue: | 3 |
ISSN: | 0733-8635 |
Publisher: | W.B. Saunders Co. |
Date Published: | 2012-07-01 |
Start Page: | 525 |
End Page: | 533 |
Language: | English |
DOI: | 10.1016/j.det.2012.04.011 |
PROVIDER: | scopus |
PUBMED: | 22800556 |
PMCID: | PMC4667364 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 August 2012" - "CODEN: DRMCD" - "Source: Scopus" |