Radiation therapy for cutaneous melanoma Journal Article

   


Authors: Barker, C. A.; Lee, N. Y.
Article Title: Radiation therapy for cutaneous melanoma
Abstract: Radiation therapy is used infrequently for cutaneous melanoma, despite research suggesting benefit in certain clinical scenarios. This review presents data forming the highest level of evidence supporting the use of radiation therapy. Retrospective and prospective studies demonstrate radiation therapy for primary tumors is associated with high control rates. Two randomized trials have found improvements in regional control with adjuvant radiotherapy to regional lymphatics. Retrospective and prospective studies demonstrate radiation therapy is associated with palliative response and metastatic tumor control. Optimal care of melanoma patients involves radiation therapy; awareness of this is incumbent of clinicians caring for patients with this disease. © 2012 Elsevier Inc.
Keywords: drug tolerability; review; bone metastasis; cancer radiotherapy; comparative study; recurrence risk; lymph node metastasis; lymphatic metastasis; evidence-based medicine; melanoma; neoplasm recurrence, local; skin neoplasms; lentigo maligna; malignant lentigo; hutchinson's melanotic freckle; retrospective study; distant metastasis; lymphedema; patient care; brain metastasis; radiation therapy; desmoplastic melanoma; stereotactic radiosurgery; cancer control; skin metastasis; cutaneous melanoma; palliation; high-risk; adjuvant; parotitis; nodal recurrence; malignant lentigo melanoma
Journal Title: Dermatologic Clinics
Volume: 30
Issue: 3
ISSN: 0733-8635
Publisher: W.B. Saunders Co.  
Date Published: 2012-07-01
Start Page: 525
End Page: 533
Language: English
DOI: 10.1016/j.det.2012.04.011
PROVIDER: scopus
PUBMED: 22800556
PMCID: PMC4667364
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84863867655&partnerID=40&md5=2d38717add1474a04a4049a65ef57165
Notes: --- - "Export Date: 1 August 2012" - "CODEN: DRMCD" - "Source: Scopus"
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MSK Authors
  1. Nancy Y. Lee
    877 Lee
  2. Christopher Barker
    218 Barker
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