Missed opportunities: Racial disparities in adjuvant breast cancer treatment Journal Article


Authors: Bickell, N. A.; Wang, J. J.; Oluwole, S.; Schrag, D.; Godfrey, H.; Hiotis, K.; Mendez, J.; Guth, A. A.
Article Title: Missed opportunities: Racial disparities in adjuvant breast cancer treatment
Abstract: Purpose Underuse of adjuvant therapy is a potentially important and remediable explanation for the inferior survival of minority women with breast cancer. We sought to measure a racial disparity in the underuse of adjuvant treatments for early-stage breast cancer and to identify associated factors. Methods Cross-sectional study with review of all inpatient and outpatient medical records of 677 women treated surgically for a primary American Joint Committee on Cancer stage I or 11 breast cancer in 1999 to 2000. Underuse was defined as omissions of radiation therapy after breast-conserving surgery, adjuvant chemotherapy after resection of hormone-receptor-negative tumors I cm, or hormonal therapy for receptor-positive tumors >= 1 cm. Results One hundred forty-five (21%) of 677 women experienced underuse of appropriate adjuvant therapy: 16% in whites, 34% in blacks, and 23% in Hispanics (P < .001). Women referred to medical oncologists were less likely to experience underuse of necessary adjuvant treatments (relative risk [RR] for underuse = 0.2; 95% Cl, 0.1 to 0.3). Women who were minorities (RR = 2.0; 95% CI, 1.3 to 3.1), had higher levels of comorbidity (RR = 1.4-1 95% CI, 1.1 to 1.8) and lacked insurance (RR = 1.9; 95% CI, 0.9 to 4.0) were at greater risk for underuse. Conclusion Minority women with early-stage breast cancer have double the risk of white women for failing to receive necessary adjuvant treatments despite rates of oncologic consultation similar to those for white women. Oncology referrals are necessary to reduce treatment disparities but are not sufficient to ensure patients' receipt of efficacious adjuvant treatment.
Keywords: survival; chemotherapy; diagnosis; comorbidity; carcinoma; stage; care; older; quality; black-and-white
Journal Title: Journal of Clinical Oncology
Volume: 24
Issue: 9
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2006-03-20
Start Page: 1357
End Page: 1362
Language: English
ACCESSION: WOS:000236501100007
DOI: 10.1200/jco.2005.04.5799
PROVIDER: wos
PUBMED: 16549830
Notes: --- - Article - "Source: Wos"
Altmetric
Citation Impact
MSK Authors
  1. Jane E. Mendez
    7 Mendez
  2. Deborah Schrag
    146 Schrag
  3. Jane Jian Wang
    7 Wang