Cancer- and chemotherapy-induced anemia: Clinical practice guidelines in oncology Journal Article
| Authors: | Rodgers, G. M. 3rd; Becker, P. S.; Blinder, M.; Cella, D.; Chanan-Khan, A.; Cleeland, C.; Coccia, P. F.; Djulbegovic, B.; Gilreath, J. A.; Kraut, E. H.; Matulonis, U. A.; Millenson, M. M.; Reinke, D.; Rosenthal, J.; Schwartz, R. N.; Soff, G.; Stein, R. S.; Vlahovic, G.; Weir, A. B. 3rd |
| Article Title: | Cancer- and chemotherapy-induced anemia: Clinical practice guidelines in oncology |
| Abstract: | Anemia is prevalent in 30% to 90% of patients with cancer. Anemia can be corrected through either treating the underlying cause or providing supportive care through transfusion with packed red blood cells or administration of erythropoiesis-stimulating agents (ESAs), with or without iron supplementation. Recent studies showing detrimental health effects of ESAs sparked a series of FDA label revisions and a sea change in the perception of these once commonly used agents. In light of this, the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer- and Chemotherapy-Induced Anemia underwent substantial revisions this year. The purpose of these NCCN Guidelines is twofold: 1) to operationalize the evaluation and treatment of anemia in adult cancer patients, with an emphasis on those who are receiving concomitant chemotherapy, and 2) to enable patients and clinicians to individualize anemia treatment options based on patient condition. © JNCCN-Journal of the National Comprehensive Cancer Network. |
| Keywords: | cancer chemotherapy; cancer survival; treatment response; primary tumor; overall survival; antianemic agent; fatigue; mortality; review; drug efficacy; risk benefit analysis; antineoplastic agents; cancer patient; cancer radiotherapy; antineoplastic agent; clinical practice; neoplasms; anemia; erythropoiesis; risk factors; hemoglobin; hematopoietic stem cell transplantation; food and drug administration; radiation exposure; risk assessment; dyspnea; syncope; drug induced headache; thorax pain; health status; vein thrombosis; blood transfusion; medical oncology; mean corpuscular volume; tumor growth; erythrocyte transfusion; recombinant erythropoietin; ferritin; drug exposure; transferrin; critically ill patient; vertigo; novel erythropoiesis stimulating protein; hematinics; menstruation disorder; ferric gluconate; ferric hydroxide sucrose; iron dextran; arterial thromboembolism; chemotherapy induced anemia |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 10 |
| Issue: | 5 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2012-05-01 |
| Start Page: | 628 |
| End Page: | 653 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 22570293 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 July 2012" - "Source: Scopus" |
