Hodgkin lymphoma, version 2.2012: Featured updates to the NCCN guidelines Journal Article


Authors: Hoppe, R. T.; Advani, R. H.; Ai, W. Z.; Ambinder, R. F.; Aoun, P.; Bello, C. M.; Bierman, P. J.; Blum, K. A.; Chen, R.; Dabaja, B.; Duron, Y.; Forero, A.; Gordon, L. I.; Hernandez-Ilizaliturri, F. J.; Hochberg, E. P.; Maloney, D. G.; Mansur, D.; Mauch, P. M.; Metzger, M.; Moore, J. O.; Morgan, D.; Moskowitz, C. H.; Poppe, M.; Pro, B.; Winter, J. N.; Yahalom, J.; Sundar, H.
Article Title: Hodgkin lymphoma, version 2.2012: Featured updates to the NCCN guidelines
Abstract: The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Hodgkin Lymphoma (HL) include the clinical management of classical HL and lymphocyte-predominant HL (LPHL). Major changes have been incorporated into these guidelines since their inception. In the 2012 NCCN Guidelines for HL, PET scans are not recommended for interim restaging of patients with stage I to II favorable disease. After reevaluating the available evidence on the use of interim PET imaging, the panel recommends the use of diagnostic CT scan of involved sites for interim restaging after completion of chemotherapy for this group of patients. Maintenance rituximab for 2 years is included as an option for patients with stage IB to IIB or stage III to IV LPHL treated with rituximab alone in the first-line setting. Brentuximab vedotin is included as an option for patients with progressive disease or relapsed disease after second-line chemotherapy or high-dose therapy with autologous stem cell rescue. © JNCCN-Journal of the National Comprehensive Cancer Network.
Keywords: cancer chemotherapy; event free survival; prednisone; review; doxorubicin; cancer combination chemotherapy; antineoplastic agents; cancer radiotherapy; rituximab; positron emission tomography; neoplasm staging; dacarbazine; progression free survival; computer assisted tomography; multiple cycle treatment; etoposide; cyclophosphamide; vincristine; autologous stem cell transplantation; practice guideline; procarbazine; vinblastine; hodgkin disease; positron-emission tomography; medical oncology; bleomycin; cancer relapse; brentuximab vedotin
Journal Title: Journal of the National Comprehensive Cancer Network
Volume: 10
Issue: 5
ISSN: 1540-1405
Publisher: Harborside Press  
Date Published: 2012-05-01
Start Page: 589
End Page: 597
Language: English
PROVIDER: scopus
PUBMED: 22570290
DOI: 10.6004/jnccn.2012.0061
DOI/URL:
Notes: --- - "Export Date: 2 July 2012" - "Source: Scopus"
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  1. Joachim Yahalom
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  2. Craig Moskowitz
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