Authors: | Saslow, D.; Solomon, D.; Lawson, H. W.; Killackey, M.; Kulasingam, S. L.; Cain, J.; Garcia, F. A. R.; Moriarty, A. T.; Waxman, A. G.; Wilbur, D. C.; Wentzensen, N.; Downs, L. S. Jr; Spitzer, M.; Moscicki, A. B.; Franco, E. L.; Stoler, M. H.; Schiffman, M.; Castle, P. E.; Myers, E. R. |
Article Title: | American Cancer Society, American Society for Colposcopy and Cervical Pathology, and American Society for Clinical Pathology screening guidelines for the prevention and early detection of cervical cancer |
Abstract: | An update to the American Cancer Society (ACS) guideline regarding screening for the early detection of cervical precancerous lesions and cancer is presented. The guidelines are based on a systematic evidence review, contributions from 6 working groups, and a recent symposium cosponsored by the ACS, the American Society for Colposcopy and Cervical Pathology, and the American Society for Clinical Pathology, which was attended by 25 organizations. The new screening recommendations address age-appropriate screening strategies, including the use of cytology and high-risk human papillomavirus (HPV) testing, follow-up (eg, the management of screen positives and screening intervals for screen negatives) of women after screening, the age at which to exit screening, future considerations regarding HPV testing alone as a primary screening approach, and screening strategies for women vaccinated against HPV16 and HPV18 infections. Cervical cancer screening has successfully decreased cervical cancer incidence and mortality. The American Cancer Society (ACS) guideline for the early detection of cervical cancer was last reviewed and updated in 2002; for the first time, those recommendations incorporated human papillomavirus (HPV) DNA testing.1 Since that time, numerous studies have been published that support changes to recommended age-appropriate screening as well as the management of abnormal screening results, as summarized in Table 1. Copyright© by the American Society for Clinical Pathology. |
Keywords: | cancer survival; cancer risk; risk benefit analysis; follow up; methodology; cancer diagnosis; cancer incidence; hysterectomy; diagnostic accuracy; sensitivity and specificity; cancer prevention; cancer screening; mass screening; practice guideline; pathology; cancer mortality; groups by age; risk assessment; virology; standard; early diagnosis; uterine cervix cancer; cancer immunization; consensus development; virus infection; high risk population; uterine cervical neoplasms; isolation and purification; early detection of cancer; uterine cervix tumor; uterine cervix cytology; cytodiagnosis; colposcopy; wart virus; uterine cervix carcinoma in situ; vagina smear; cervical intraepithelial neoplasia; papillomavirus infections; vaginal smears; non profit organization; uterus carcinoma; papilloma virus; papanicolaou test; wart virus vaccine; papillomavirus infection; vagina cancer; human papillomavirus type 16; human papillomavirus type 18; papillomaviridae |
Journal Title: | American Journal of Clinical Pathology |
Volume: | 137 |
Issue: | 4 |
ISSN: | 0002-9173 |
Publisher: | Oxford University Press |
Date Published: | 2012-04-01 |
Start Page: | 516 |
End Page: | 542 |
Language: | English |
DOI: | 10.1309/ajcptgd94evrsjcg |
PROVIDER: | scopus |
PUBMED: | 22431528 |
DOI/URL: | |
Notes: | --- - "Export Date: 4 June 2012" - "CODEN: AJCPA" - "Source: Scopus" |