A 4DRT simulation study using a synthetic 3.5D CT image with motion-free target of lung cancer based on 4DCT Journal Article


Authors: Li, G.; Xie, H.; Ning, H.; Arora, N.; Brown, A.; Guion, P.; Cheng, J.; Arora, B.; Kaushal, A.; Citrin, D.; Camphausen, K.; Miller, R. W.
Article Title: A 4DRT simulation study using a synthetic 3.5D CT image with motion-free target of lung cancer based on 4DCT
Abstract: Four-Dimensional Radiotherapy (4DRT) planning based on 4D Computed Tomography (4DCT) is limited by drastically increased planning workload and unavoidably needed new software. We introduced a new concept of 3.5DCT for a simplified 4DRT planning. This 3.5DCT is synthesized from 4DCT by aligning the tumour centres in each phase, simulating a motion-compensated tumour from the beam eye's view. Four patients' 4DCTs were used for the 4DRT planning, which were compared with motion-trajectory-based and respiratory-gated plans. This simplified 4DRT plan shows dosimetric advantage of significant reduction of V95 and V20. This suggests that the static 3.5DCT image is sufficient for 4DRT planning. Copyright © 2012 Inderscience Enterprises Ltd.
Keywords: treatment planning; radiotherapy; patient monitoring; computerized tomography; medical imaging; tumors; computed tomography; 4dct; 4drt; respiratory motion tracking; 4D computed tomography; 4DRT treatment planning; four-dimensional radiation therapy
Journal Title: International Journal of Biomedical Engineering and Technology
Volume: 8
Issue: 2-3
ISSN: 1752-6418
Publisher: Inderscience Publishers  
Date Published: 2012-01-01
Start Page: 167
End Page: 181
Language: English
DOI: 10.1504/IJBET.2012.046084
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 4 June 2012" - "Source: Scopus" - Special Issue on 4D Medical Imaging and 4D Radiation Therapy
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  1. Guang Li
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