An update on risk factors, prognosis and management of melanoma patients Journal Article


Authors: Jaimes, N.; Marghoob, A. A.
Article Title: An update on risk factors, prognosis and management of melanoma patients
Abstract: Cutaneous melanoma continues to be a public health problem worldwide and its incidence continues to increase around the globe. The recognition of melanoma risk factors allows for the identification of a subgroup of high-risk patients that will likely benefit most from approaches aimed at minimizing exposure to ultraviolet radiation and from surveillance strategies geared towards finding melanomas while thin and easily curable. Herein, we will provide an overview of the most pertinent, novel and newly described melanoma risk factors and melanoma prognostic factors. The potential benefits of skin cancer surveillance strategies including physician-based total body skin examination, total body photography, dermoscopy and patient-based self-skin examination will be examined. In addition, management of melanoma patients, focusing on prevention and early detection strategies will be discussed.
Keywords: mitogen activated protein kinase; gene mutation; review; interferon; cancer patient; cancer diagnosis; dacarbazine; interleukin 2; sunscreen; cancer immunotherapy; cancer prevention; low drug dose; melanoma; sun exposure; nevus; risk factors; brca2 protein; phosphatidylinositol 3 kinase; risk factor; epiluminescence microscopy; melanocytic nevus; early diagnosis; acetylsalicylic acid; cyclooxygenase 2 inhibitor; nonsteroid antiinflammatory agent; skin examination; phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase; antioxidant; dysplastic nevus; medical photography; cyclin dependent kinase inhibitor 2a; parkinson disease; ultraviolet rays; melanocortin 1 receptor; xeroderma pigmentosum; primary prevention; congenital nevus; cyclin dependent kinase 4; puva; vemurafenib; cancer prognosis; non melanoma skin cancer
Journal Title: Giornale Italiano di Dermatologia e Venereologia
Volume: 147
Issue: 1
ISSN: 0392-0488
Publisher: Edizioni Minerva Medica  
Date Published: 2012-02-01
Start Page: 1
End Page: 19
Language: English
PROVIDER: scopus
PUBMED: 22370565
DOI/URL:
Notes: --- - "Export Date: 4 June 2012" - "CODEN: GIDVD" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Ashfaq A Marghoob
    534 Marghoob