High rates of surveillance imaging for treated diffuse large B-cell lymphoma: Findings from a large national database Journal Article
| Authors: | Abel, G. A.; Vanderplas, A.; Rodriguez, M. A.; Crosby, A. L.; Czuczman, M. S.; Niland, J. C.; Gordon, L. I.; Millenson, M.; Zelenetz, A. D.; Friedberg, J. W.; LaCasce, A. S. |
| Article Title: | High rates of surveillance imaging for treated diffuse large B-cell lymphoma: Findings from a large national database |
| Abstract: | We aimed to characterize surveillance imaging and circumstances of relapse for patients with diffuse large B-cell lymphoma (DLBCL) in the National Comprehensive Cancer Network Non-Hodgkin's Lymphoma Outcomes Database, a prospective cohort study collecting clinical and outcome data at seven comprehensive cancer centers. Patients presenting with newly diagnosed DLBCL in remission ≥3 months after initial therapy and who had accrued 2 years of follow-up were eligible for analysis (n 625). The median number of imaging studies was 2.5/year (institutional range 0.53.5, p < 0.0001); 48.4% received only dedicated computed tomography (CT) scans, 14.6% received only positron emission tomography (PET)-inclusive modalities, 32.8% received a combination and 4.2% received no imaging. Among all eligible patients, 50 (8.0%) experienced relapse, and approximately one-quarter of subclinical relapses were detected through routine imaging. Our results suggest that despite limited data regarding its effect on outcomes, surveillance imaging is prevalent in DLBCL, and a majority of patients receive PET scans at some point during follow-up. © 2012 Informa UK, Ltd. |
| Keywords: | adult; middle aged; major clinical study; united states; positron emission tomography; follow up; follow-up studies; physician's practice patterns; computer assisted tomography; cohort studies; image analysis; evidence based practice; recurrence; tomography, x-ray computed; diagnostic imaging; data base; cancer center; cancer regression; watchful waiting; positron-emission tomography; health services research; cancer relapse; large cell lymphoma; lymphoma, large b-cell, diffuse; databases, factual; population surveillance; diffuse large b-cell lymphoma |
| Journal Title: | Leukemia and Lymphoma |
| Volume: | 53 |
| Issue: | 6 |
| ISSN: | 1042-8194 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2012-06-01 |
| Start Page: | 1113 |
| End Page: | 1116 |
| Language: | English |
| DOI: | 10.3109/10428194.2011.639882 |
| PROVIDER: | scopus |
| PUBMED: | 22098406 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 1" - "Export Date: 4 June 2012" - "CODEN: LELYE" - "Source: Scopus" |
