Toward the synthesis of xestocyclamine A: investigation of double Michael reaction and direct aza Diels-Alder reaction Journal Article
| Authors: | Yun, H.; Gagnon, A.; Danishefsky, S. J. |
| Article Title: | Toward the synthesis of xestocyclamine A: investigation of double Michael reaction and direct aza Diels-Alder reaction |
| Abstract: | An efficient synthesis of the isoquinuclidone core of xestocyclamine A is described. The key step is a direct aza Diels-Alder reaction of enone 14 and p-anisidine to assemble the isoquinuclidone core of xestocyclamine A. © 2006. |
| Keywords: | unclassified drug; drug structure; enzyme inhibitor; drug synthesis; thermodynamics; diels alder reaction; reaction analysis; chemical reaction; stereochemistry; proton nuclear magnetic resonance; cycloaddition; diastereoisomer; annulation reaction; michael addition; anisic acid; quinuclidine derivative; xestocyclamine a; suzuki reaction; betulaceae |
| Journal Title: | Tetrahedron Letters |
| Volume: | 47 |
| Issue: | 30 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2006-07-24 |
| Start Page: | 5311 |
| End Page: | 5315 |
| Language: | English |
| DOI: | 10.1016/j.tetlet.2006.05.126 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 4 June 2012" - "CODEN: TELEA" - "Source: Scopus" |
