Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis Journal Article
| Authors: | Yang, Y. C.; Lu, M. L.; Rao, J. Y.; Wallerand, H.; Cai, L.; Cao, W.; Pantuck, A.; Dalbagni, G.; Reuter, V.; Figlin, R. A.; Belldegrun, A.; Cordon-Cardo, C.; Zhang, Z. F. |
| Article Title: | Joint association of polymorphism of the FGFR4 gene and mutation TP53 gene with bladder cancer prognosis |
| Abstract: | The impact of the fibroblast growth factor receptor 4 (FGFR4) Gly388Arg polymorphism on bladder cancer is unknown. We found no clear correlations between the FGFR4 genotype and risk of bladder cancer or pathological parameters. Neither the polymorphism nor TP53 mutation status was an independent predictor of prognosis, but they might act jointly on the disease-specific survival of patients. © 2006 Cancer Research. |
| Keywords: | adult; cancer survival; controlled study; aged; middle aged; survival analysis; survival rate; gene mutation; major clinical study; single nucleotide polymorphism; mutation; polymorphism, single nucleotide; cancer risk; genetic association; genotype; bladder cancer; protein p53; urinary bladder neoplasms; survival time; dna mutational analysis; genetic risk; genes, p53; tp53 mutation; fibroblast growth factor receptor 4; receptor, fibroblast growth factor, type 4 |
| Journal Title: | British Journal of Cancer |
| Volume: | 95 |
| Issue: | 11 |
| ISSN: | 0007-0920 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2006-12-04 |
| Start Page: | 1455 |
| End Page: | 1458 |
| Language: | English |
| DOI: | 10.1038/sj.bjc.6603456 |
| PUBMED: | 17088904 |
| PROVIDER: | scopus |
| PMCID: | PMC2360734 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 12" - "Export Date: 4 June 2012" - "CODEN: BJCAA" - "Source: Scopus" |
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