Authors: | Wyatt, A. J.; Agero, A. L. C.; Delgado, R.; Busam, K. J.; Marghoob, A. A. |
Article Title: | Cutaneous metastatic breast carcinoma with melanocyte colonization: A clinical and dermoscopic mimic of malignant melanoma |
Abstract: | BACKGROUND: Melanocyte colonization of breast carcinoma cells may occur in those tumors that breach the epidermal - dermal interface. The resultant melanin deposition in tumor cells rarely leads to clinical pigmentation of the tumor. Typically, selective staining methods are required to detect the pigment. OBSERVATION: The authors describe a 60-year-old woman with a history of mammary carcinoma and an irregularly pigmented nodule with peripheral globules and a blue-white veil on dermoscopy, which was a clinical and dermoscopic mimic of malignant melanoma. CONCLUSIONS: Awareness of melanocyte colonization of non-melanocytic tumor cells and the dermoscopic - histologic correlations can aid in avoiding a potential pitfall, and emphasize the importance of such relationships, when using this tool. © 2006 by the American Society for Dermatologic Surgery, Inc. Published by Blackwell Publishing. |
Keywords: | immunohistochemistry; adult; middle aged; clinical feature; disease course; histopathology; case report; adenocarcinoma; diagnostic procedure; melanoma; dermoscopy; skin neoplasms; melanocyte; diagnosis, differential; melanocytes; differential diagnosis; breast neoplasms; epiluminescence microscopy; correlation analysis; laboratory test; breast carcinoma; skin metastasis |
Journal Title: | Dermatologic Surgery |
Volume: | 32 |
Issue: | 7 |
ISSN: | 1076-0512 |
Publisher: | Lippincott Williams & Wilkins |
Date Published: | 2006-07-01 |
Start Page: | 949 |
End Page: | 954 |
Language: | English |
DOI: | 10.1111/j.1524-4725.2006.32202.x |
PUBMED: | 16875480 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 8" - "Export Date: 4 June 2012" - "CODEN: DESUF" - "Source: Scopus" |