Gastric cancer: An update Journal Article
| Author: | Shah, M. A. |
| Article Title: | Gastric cancer: An update |
| Abstract: | Gastric cancer is an aggressive malignancy, which, if metastatic or unresectable, is incurable. However, with metastatic or unresectable disease, patients receive a palliative benefit from chemotherapy. Although the understanding of the biology of this disease is increasing, the development of biologically targeted therapies for gastric cancer has been limited. Cytotoxic therapy remains the standard approach, and although there is agreement on the active agents and active combination chemotherapy regimens, consensus on the standard or reference regimen is lacking. This article reviews the pathophysiology of this disease, placing it in the context of its epidemiology, and the current advances in the treatment of this disease. Copyright © 2006 by Current Science Inc. |
| Keywords: | vasculotropin; cancer survival; clinical trial; drug tolerability; neutropenia; review; bevacizumab; cisplatin; cytotoxic agent; doxorubicin; fluorouracil; cancer combination chemotherapy; drug efficacy; pathophysiology; capecitabine; methotrexate; antineoplastic agent; cancer palliative therapy; palliative care; consensus; metastasis; infection; bone marrow suppression; etoposide; blood toxicity; nausea; neuropathy; stomatitis; vomiting; antineoplastic combined chemotherapy protocols; antineoplastic activity; cetuximab; uvomorulin; docetaxel; irinotecan; febrile neutropenia; drug delivery systems; standard; gastrointestinal toxicity; thromboembolism; folinic acid; gefitinib; neoplasm metastasis; medical oncology; malignant neoplastic disease; stomach cancer; epirubicin; mitomycin c; molecular biology; oxaliplatin; lethargy; digestive system perforation; wnt protein; stomach neoplasms; apc protein; tegafur; matuzumab; 5 chloro 2,4 dihydroxypyridine plus oxonate potassium plus tegafur; uracil |
| Journal Title: | Current Oncology Reports |
| Volume: | 8 |
| Issue: | 3 |
| ISSN: | 1523-3790 |
| Publisher: | Springer |
| Date Published: | 2006-05-01 |
| Start Page: | 183 |
| End Page: | 191 |
| Language: | English |
| DOI: | 10.1007/s11912-006-0018-4 |
| PUBMED: | 16618382 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 4 June 2012" - "CODEN: CORUA" - "Source: Scopus" |
