Intraflagellar transport and cilium-based signaling Journal Article
| Authors: | Scholey, J. M.; Anderson, K. V. |
| Article Title: | Intraflagellar transport and cilium-based signaling |
| Abstract: | Cilia are specialized structures that not only play diverse roles in cell motility but also transmit signals to the cytoplasm and nucleus to control gene expression, cell function, animal development, and behavior. Cilia are assembled and maintained by the intraflagellar transport (IFT) machinery, which coordinates rapid, bidirectional transport between the cell body and the distal tip of the cilium. A new study (Wang et al., 2006) illuminates the role of IFT in cilium-based signaling during mating in the alga Chlamydomonas. © 2006 Elsevier Inc. All rights reserved. |
| Keywords: | signal transduction; nonhuman; protein function; animal; animals; cell function; sonic hedgehog protein; hedgehog proteins; developmental biology; animalia; vertebrata; gene expression regulation; eukaryota; protein transport; cytoplasm; short survey; cell polarity; behavior; trans-activators; cell nucleus; nerve cell; erinaceidae; vertebrate; signal processing; cell motility; eukaryotic flagellum; body patterning; cilia; flagella; sensory receptor; chlamydomonas; flagellum; kinetosome; algae; alga; mating; molecular motor proteins; sexual behavior, animal |
| Journal Title: | Cell |
| Volume: | 125 |
| Issue: | 3 |
| ISSN: | 0092-8674 |
| Publisher: | Cell Press |
| Date Published: | 2006-05-05 |
| Start Page: | 439 |
| End Page: | 442 |
| Language: | English |
| DOI: | 10.1016/j.cell.2006.04.013 |
| PUBMED: | 16678091 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 104" - "Export Date: 4 June 2012" - "CODEN: CELLB" - "Source: Scopus" |
