Partial nephrectomy achieves local tumor control and prevents chronic kidney disease Journal Article
| Author: | Russo, P. |
| Article Title: | Partial nephrectomy achieves local tumor control and prevents chronic kidney disease |
| Abstract: | Over the last 10 years, a rapidly changing clinical landscape has created an optimal environment to expand the use of partial nephrectomy for the treatment of renal cortical tumors. The main factors responsible for the increasing use of partial nephrectomy relate to the appreciation of the diversity of renal cortical tumor histology, the tumor stage and size migration associated with their incidental detection, and the oncological efficacy of partial nephrectomy for tumors of 7 cm or smaller. Evidence has now emerged that radical nephrectomy performed during the treatment of a small renal mass may further reduce an already impaired baseline renal function and place the patient in the realm of chronic kidney disease. Important new information concerning chronic kidney disease, a condition far more prevalent in the aging US population than previously appreciated, and its associated cardiovascular morbidity and mortality, now places maximal renal functional preservation on a par with local tumor as surgical plans are formulated for the resection of a small renal cortical tumor. © 2006 Future Drugs Ltd. |
| Keywords: | treatment outcome; surgical technique; histopathology; mortality; review; united states; cancer patient; cancer staging; laparoscopic surgery; tumor volume; morbidity; prevalence; carcinoma, papillary; creatinine; creatinine blood level; adenoma, oxyphilic; kidney neoplasms; nephrectomy; postoperative complications; chronic disease; tissue donors; partial nephrectomy; kidney tumor; carcinoma, renal cell; kidney function; chronic kidney disease; kidney injury; cardiovascular risk; cardiovascular diseases; glomerulus filtration rate; minimally invasive surgery; incidental finding; adenocarcinoma, clear cell; cancer control; kidney transplantation; kidney cortex; kidney function tests; kidney diseases; kidney tumors; kidney donor |
| Journal Title: | Expert Review of Anticancer Therapy |
| Volume: | 6 |
| Issue: | 12 |
| ISSN: | 1473-7140 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2006-12-01 |
| Start Page: | 1745 |
| End Page: | 1751 |
| Language: | English |
| DOI: | 10.1586/14737140.6.12.1745 |
| PUBMED: | 17181488 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 6" - "Export Date: 4 June 2012" - "CODEN: ERATB" - "Source: Scopus" |
