Classification and prevalence of pigmented lesions in patients with total-body photographs at high risk of developing melanoma Journal Article


Authors: Menon, K.; Dusza, S. W.; Marghoob, A. A.; Halpern, A. C.; Nehal, K. S.
Article Title: Classification and prevalence of pigmented lesions in patients with total-body photographs at high risk of developing melanoma
Abstract: Background: The classification of many pigmented lesions is not well defined, and an association with melanoma has not been established. Objective: To better define the spectrum of pigmented lesions (excluding common and dysplastic nevi) and explore links to melanoma. Methods: Retrospective review of patients with total-body digital photographs at high risk of developing melanoma from the Memorial Sloan-Kettering Cancer Center Dermatology Service. Results: Among 598 patients, 7.7% had café au lait spots, 2.8% had nevi spilus, 2.3% had congenital nevus-like nevi, 2% had "other" lesions, 1.2% had segmental speckled lentiginous nevi, and 1% had agminated nevi. There was no statistical difference in the prevalence rates of these pigmented lesions in patients with or without a history of melanoma or ≥ 100 nevi. Conclusions: A wide range of pigmented lesions require further classification and study to explore possible links to melanoma.
Keywords: adolescent; adult; child; school child; aged; middle aged; retrospective studies; major clinical study; anamnesis; cancer risk; disease classification; melanoma; skin pigmentation; skin neoplasms; diagnosis, differential; differential diagnosis; prevalence; pathology; retrospective study; risk assessment; cancer center; skin tumor; statistical analysis; nevus, pigmented; dysplastic nevus; photography; cafe au lait spot; digital imaging; pigmented nevus
Journal Title: Journal of Cutaneous Medicine and Surgery
Volume: 10
Issue: 2
ISSN: 1203-4754
Publisher: B C Decker Inc  
Date Published: 2006-03-01
Start Page: 85
End Page: 91
Language: English
DOI: 10.2310/7750.2006.00024
PUBMED: 17241580
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 7" - "Export Date: 4 June 2012" - "CODEN: JCMSF" - "Source: Scopus"
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MSK Authors
  1. Allan C Halpern
    396 Halpern
  2. Kishwer S Nehal
    278 Nehal
  3. Stephen Dusza
    288 Dusza
  4. Ashfaq A Marghoob
    534 Marghoob