Extrapleural pneumonectomy in children Journal Article
| Authors: | Flores, R. M.; Su, W.; Lal, D.; Rusch, V. W.; La Quaglia, M. P. |
| Article Title: | Extrapleural pneumonectomy in children |
| Abstract: | Background/Purpose: Extrapleural pneumonectomy (EPP) is an en bloc resection of the pleura, lung, diaphragm, and pericardium. EPP in the pediatric population has not been reported in the literature. We report our experience of using EPP in children to treat a variety of malignancies that involve the pleural surface. Methods: We performed a retrospective review of all children treated through EPP at our institution. Data were obtained from patient charts and a pediatric database. All patients underwent en bloc resection of the pleura, lung, diaphragm, and pericardium and reconstruction. Results: Four patients underwent EPP from 2000 to 2004 for inflammatory myofibroblastic tumor, spindle cell sarcoma, metastatic neuroblastoma, and malignant mesothelioma. The patients' ages were from 6 to 11 years. The patient with metastatic neuroblastoma had recurrent disease in the left chest 1 year after EPP and died of sepsis; the patient with mesothelioma died of disease extension into the abdomen 1.5 years later. The other 2 patients are free of disease. Conclusions: EPP can be performed with curative intent in selected pediatric patients with pleural-based malignancies. EPP should be included in the armamentarium of the pediatric thoracic surgeon and evaluated in larger studies. © 2006 Elsevier Inc. All rights reserved. |
| Keywords: | child; retrospective studies; case report; cancer patient; metastasis; lung resection; pneumonectomy; medical record review; retrospective study; reference database; pediatric; sarcoma; cause of death; abdomen; neuroblastoma; lung; malignant mesothelioma; mesothelioma; recurrent disease; sepsis; spindle cell sarcoma; diaphragm; extrapleural pneumonectomy; pleurectomy; pericardium; pleura; thorax disease; pleural neoplasms; heart surgery; pleura cancer; plasma cell granuloma; abdominal neoplasms; granuloma, plasma cell; inflammatory myofibroblastic tumor; pleural diseases |
| Journal Title: | Journal of Pediatric Surgery |
| Volume: | 41 |
| Issue: | 10 |
| ISSN: | 0022-3468 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2006-10-01 |
| Start Page: | 1738 |
| End Page: | 1742 |
| Language: | English |
| DOI: | 10.1016/j.jpedsurg.2006.05.063 |
| PUBMED: | 17011280 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 June 2012" - "CODEN: JPDSA" - "Source: Scopus" |
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