Palliative percutaneous drainage in malignant biliary obstruction - Part 2: Mechanisms and postprocedure management Journal Article


Authors: Covey, A. M.; Brown, K. T.
Article Title: Palliative percutaneous drainage in malignant biliary obstruction - Part 2: Mechanisms and postprocedure management
Abstract: Malignant biliary obstruction frequently is associated with pruritus, anorexia, cholangitis, or hyperbilirubinemia; this difficult complication precludes the use of antineoplastic agents that are excreted or metabolized via the liver. In patients with low biliary obstruction, endoscopic stent placement may accomplish drainage of the entire biliary tree without the need for an external device. However, patients with high bile duct obstruction most often require a percutaneous approach to drain the target ducts to maximize drainage and to avoid draining an atrophic segment or lobe. In the first in this series of two articles, the indications for biliary drainage and preprocedure evaluation in malignant biliary obstruction were discussed. This second article describes the mechanisms of percutaneous biliary drainage and postprocedure management, including consideration of possible complications. © 2006 Elsevier Inc. All rights reserved.
Keywords: treatment outcome; antibiotic agent; review; ascites; postoperative care; antineoplastic agent; preoperative evaluation; anorexia; cancer palliative therapy; treatment indication; palliative care; disease association; quality of life; computer assisted tomography; midazolam; opiate; tomography, x-ray computed; patient monitoring; surgical approach; colorectal carcinoma; fever; pruritus; postoperative complication; bilirubin; hypotension; disease severity; rigor; echography; radiography, interventional; postoperative infection; sepsis; stent; intermethod comparison; clinical pathway; bile duct carcinoma; bile duct neoplasms; hyperbilirubinemia; bacteremia; drug metabolism; bile duct obstruction; biliary tract drainage; postoperative hemorrhage; life expectancy; drug excretion; percutaneous drainage; drainage; cholestasis; stents; artery injury; catheter; isolation procedure; hemobilia; short acting drug; cholangitis; dental anesthesia; endoleak
Journal Title: The Journal of Supportive Oncology
Volume: 4
Issue: 7
ISSN: 1544-6794
Publisher: BioLink Communications  
Date Published: 2006-07-01
Start Page: 329
End Page: 335
Language: English
PUBMED: 16892694
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 11" - "Export Date: 4 June 2012" - "CODEN: JSOOB" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Anne Covey
    169 Covey
  2. Karen T Brown
    178 Brown