The total synthesis of (±)-11-O-debenzoyltashironin Journal Article
| Authors: | Cook, S. P.; Polara, A.; Danishefsky, S. J. |
| Article Title: | The total synthesis of (±)-11-O-debenzoyltashironin |
| Abstract: | The total synthesis of the putative non-peptidyl neurotrophic factor 11-O-debenzoyltashironin has been accomplished. The key transformation involves a biomimetic oxidative dearomatization/transannular Diels-Alder sequence that closes the tetracyclic carbon skeleton present in the natural product. Copyright © 2006 American Chemical Society. |
| Keywords: | unclassified drug; drug activity; drug synthesis; chemistry; chemical structure; molecular structure; cyclization; natural product; oxidation; diels alder reaction; oxidation reduction reaction; oxidation-reduction; synthesis; stereoisomerism; carbon; bridged compounds; annulation reaction; aromatization; 11 o debenzoyltashironin; nerve cell growth; illicium; 11-o-debenzoyltashironin; bridged compound |
| Journal Title: | Journal of the American Chemical Society |
| Volume: | 128 |
| Issue: | 51 |
| ISSN: | 0002-7863 |
| Publisher: | American Chemical Society |
| Date Published: | 2006-12-27 |
| Start Page: | 16440 |
| End Page: | 16441 |
| Language: | English |
| DOI: | 10.1021/ja0670254 |
| PUBMED: | 17177359 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 30" - "Export Date: 4 June 2012" - "CODEN: JACSA" - "Source: Scopus" |
