Authors: | Globus, S. T.; Keeney, S. |
Article Title: | The joy of six: How to control your crossovers |
Abstract: | Meiotic cells tightly regulate the number and distribution of crossovers to promote accurate chromosome segregation. Yokoo and colleagues uncover a metazoan-specific, cyclin-like protein that is crucial for crossover formation. They utilize this protein's unique properties to explore a remarkable example of biological numerology, whereby nearly every meiotic cell in C. elegans makes precisely six crossovers, one for each of its six chromosome pairs. © 2012 Elsevier Inc. |
Keywords: | review; nonhuman; meiosis; regulatory mechanism; caenorhabditis elegans; cycline; chromosome pairing; chromosome segregation; metazoa; crossing over; metazoon |
Journal Title: | Cell |
Volume: | 149 |
Issue: | 1 |
ISSN: | 0092-8674 |
Publisher: | Cell Press |
Date Published: | 2012-03-30 |
Start Page: | 11 |
End Page: | 12 |
Language: | English |
DOI: | 10.1016/j.cell.2012.03.011 |
PROVIDER: | scopus |
PUBMED: | 22464316 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 May 2012" - "CODEN: CELLB" - "Source: Scopus" |