Authors: | Stathopoulos, C.; Brennan, N.; Peck, K. K. ; Holodny, A. I. |
Article Title: | Preoperative functional MRI of motor and sensory cortices: How imaging can save vital functions |
Abstract: | Blood oxygen level-dependent functional MRI (fMRI) has been used to enhance the understanding of neuroanatomy and functions of the brain and is becoming an accepted brain-mapping tool for clinicians, researchers and basic scientists alike. fMRI has an ever-growing list of clinical applications, including presurgical mapping of motor, language and memory functions, and has no known risks as a noninvasive procedure. fMRI data gives the neurosurgeon the opportunity to make more informed decisions regarding the approach to the tumor and the necessity for invasive mapping procedures. This article reviews the applicability of fMRI to clinical neurosurgical practice, describes the optimization of paradigm design and delivery for motor and sensory mapping and illustrates artifacts and other clinically relevant pitfalls of fMRI. © 2012 Future Medicine Ltd. |
Keywords: | cancer surgery; review; neuroimaging; preoperative evaluation; patient monitoring; registration; computer assisted diagnosis; nerve cell plasticity; data analysis; artifact; motor dysfunction; language; functional magnetic resonance imaging; motor cortex; brain mapping; brain blood flow; hemodynamics; electrostimulation; functional mri; brain tumors; neuronavigation; brain depth stimulation; neuroanatomy; motor and sensory; paradigm; bold signal; tractography; intraoperative mapping; primary motor cortex; sensorimotor function; sensory cortex |
Journal Title: | Imaging in Medicine |
Volume: | 4 |
Issue: | 1 |
ISSN: | 1755-5191 |
Publisher: | Future Medicine |
Date Published: | 2012-01-01 |
Start Page: | 77 |
End Page: | 87 |
Language: | English |
DOI: | 10.2217/iim.11.66 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 2 April 2012" - "Source: Scopus" |