Impact of androgen deprivation therapy on sexual function Journal Article


Authors: Mazzola, C. R.; Mulhall, J. P.
Article Title: Impact of androgen deprivation therapy on sexual function
Abstract: Many patients with prostate cancer for whom androgen deprivation therapy (ADT) is indicated are young and desire to remain sexually active. In such patients, the side effects of androgen therapy on sexual function can be a source of serious reduction in overall quality of life. Providing the appropriate treatment options in this patient population is therefore essential. Nevertheless, treating such patients is challenging and an understanding of the underlying mechanisms of sexual physiology and pathophysiology is crucial to optimal patient care. In this paper, we reviewed what was known regarding the effects of ADT on sexual function in animal models and we also provided a detailed review on the effects of ADT on sexual health in humans and its treatment. © 2012 AJA, SIMM & SJTU.
Keywords: castration; erectile dysfunction; androgen deprivation therapy; ejaculation; orgasm
Journal Title: Asian Journal of Andrology
Volume: 14
Issue: 2
ISSN: 1008-682X
Publisher: Aja, Simm & Sjtu  
Date Published: 2012-03-01
Start Page: 198
End Page: 203
Language: English
DOI: 10.1038/aja.2011.106
PROVIDER: scopus
PUBMED: 22231298
PMCID: PMC3735098
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 2 April 2012" - "CODEN: ASJAF" - "Source: Scopus"
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  1. John P Mulhall
    601 Mulhall
  2. Clarisse Mazzola
    16 Mazzola