Large cell neuroendocrine carcinoma of the head and neck Journal Article
| Authors: | Kusafuka, K.; Ferlito, A.; Lewis, J. S. Jr; Woolgar, J. A.; Rinaldo, A.; Slootweg, P. J.; Gnepp, D. R.; Devaney, K. O.; Travis, W. D.; Barnes, L. |
| Article Title: | Large cell neuroendocrine carcinoma of the head and neck |
| Abstract: | Large cell neuroendocrine carcinoma is a poorly differentiated neuroendocrine carcinoma that usually occurs in the lung. Although rare in the head and neck, salivary and mucosal subtypes are recognized. This article describes their characteristic light microscopic and immunohistochemical features and highlights the importance of accurate diagnosis, management and prognostic implications. © 2011 Elsevier Ltd. All rights reserved. |
| Keywords: | immunohistochemistry; review; microscopy; cancer diagnosis; diagnostic accuracy; classification; large cell carcinoma; head and neck; salivary gland carcinoma; head and neck carcinoma; thyroid transcription factor 1; synaptophysin; large cell neuroendocrine carcinoma; chromogranin a; neuroendocrine carcinomas; cd56 antigen; terminology; cancer prognosis; salivary large cell neuroendocrine carcinoma |
| Journal Title: | Oral Oncology |
| Volume: | 48 |
| Issue: | 3 |
| ISSN: | 1368-8375 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2012-03-01 |
| Start Page: | 211 |
| End Page: | 215 |
| Language: | English |
| DOI: | 10.1016/j.oraloncology.2011.09.016 |
| PROVIDER: | scopus |
| PUBMED: | 22024350 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 2 April 2012" - "CODEN: EJCCE" - "Source: Scopus" |
