Radiotherapy for liver metastases: A review of evidence Journal Article
| Authors: | Høyer, M.; Swaminath, A.; Bydder, S.; Lock, M.; Méndez Romero, A.; Kavanagh, B.; Goodman, K. A.; Okunieff, P.; Dawson, L. A. |
| Article Title: | Radiotherapy for liver metastases: A review of evidence |
| Abstract: | Over the past decade, there has been an increasing use of radiotherapy (RT) for the treatment of liver metastases. Most often, ablative doses are delivered to focal liver metastases with the goal of local control and ultimately improving survival. In contrast, low-dose whole-liver RT may be used for the palliation of symptomatic diffuse metastases. This review examines the available clinical data for both approaches. The review found that RT is effective both for local ablation of focal liver metastases and for palliation of patients with symptomatic liver metastases. However, there is a lack of a high level of evidence from randomized clinical trials. © 2012 Elsevier Inc. |
| Keywords: | cancer survival; cancer surgery; survival rate; review; cancer radiotherapy; radiation dose; outcome assessment; cancer palliative therapy; colorectal cancer; progression free survival; radiotherapy; pathology; survival time; liver metastasis; brachytherapy; medline; cancer control; stereotactic body radiation therapy; computer assisted radiotherapy; ablation therapy; liver metastases; randomized controlled trial (topic); conformal radiotherapy; phase 2 clinical trial (topic); multicenter study (topic); internal radiotherapy; cancer prognosis; selective internal radiotherapy; whole liver radiotherapy; selected internal radiotherapy |
| Journal Title: | International Journal of Radiation Oncology, Biology, Physics |
| Volume: | 82 |
| Issue: | 3 |
| ISSN: | 0360-3016 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2012-03-01 |
| Start Page: | 1047 |
| End Page: | 1057 |
| Language: | English |
| DOI: | 10.1016/j.ijrobp.2011.07.020 |
| PROVIDER: | scopus |
| PUBMED: | 22284028 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 1 March 2012" - "CODEN: IOBPD" - "Source: Scopus" |
