Hepatitis C and non-Hodgkin lymphoma: The clinical perspective Journal Article


Authors: Hartridge-Lambert, S. K.; Stein, E. M.; Markowitz, A. J.; Portlock, C. S.
Article Title: Hepatitis C and non-Hodgkin lymphoma: The clinical perspective
Abstract: Hepatitis C virus (HCV) is a commonly transmitted infection that has both hepatic and extrahepatic repercussions. These range from the inflammatory to the oncologic with an undisputed link to hepatitis, liver cirrhosis, and hepatocellular carcinoma. Its role in the development of B cell non-Hodgkin lymphoma (B-NHL) is becoming better understood, leading to opportunities for research, therapy, and even prevention. Research in the field has progressed significantly over the last decade, with the number of patients diagnosed with HCV and B-NHL rising incrementally. It is therefore becoming crucial to fully understand the pathobiologic link of HCV in B cell lymphomagenesis and its optimal management in the oncologic setting. © 2011 American Association for the Study of Liver Diseases.
Keywords: treatment outcome; overall survival; disease course; review; drug efficacy; hepatitis c; nonhuman; treatment duration; alpha interferon; disease free survival; rituximab; follow up; antineoplastic agent; cell proliferation; disease association; liver toxicity; b cell lymphoma; nonhodgkin lymphoma; disease duration; large cell lymphoma; virus load; virus replication; hepatitis c virus; virus latency; follicular lymphoma; marginal zone lymphoma; ribavirin; helicobacter pylori; peripheral blood mononuclear cell; antiviral therapy; peginterferon; mucosa associated lymphoid tissue lymphoma; cancer prognosis; boceprevir; telaprevir
Journal Title: Hepatology
Volume: 55
Issue: 2
ISSN: 0270-9139
Publisher: John Wiley & Sons  
Date Published: 2012-02-01
Start Page: 634
End Page: 641
Language: English
DOI: 10.1002/hep.25499
PROVIDER: scopus
PUBMED: 22120959
DOI/URL:
Notes: --- - "Export Date: 1 March 2012" - "CODEN: HPTLD" - "Source: Scopus"
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Carol Portlock
    204 Portlock
  2. Arnold J Markowitz
    138 Markowitz
  3. Eytan Moshe Stein
    342 Stein