A tailored occupational therapy approach to cognitive rehabilitation of chemotherapy-related cognitive side effects in breast cancer survivors: Two case studies of premenopausally affected women Journal Article

  

Authors:	Ryan, E. L.; Miskovitz, G.; Sutton, D.; Ahles, T.
Article Title:	A tailored occupational therapy approach to cognitive rehabilitation of chemotherapy-related cognitive side effects in breast cancer survivors: Two case studies of premenopausally affected women
Abstract:	This article describes a tailored occupational therapy program to rehabilitate chemothe-rapy-related cognitive side effects. A literature review of cognitive rehabilitation as well as pharmacological trials used to improve cognition in breast cancer patients is included. Two outpatient case studies of young women premenopausally affected with breast cancer (both BRCA-1 gene mutation carriers) are used to discuss the role of tailored occupational therapy techniques for developing compensatory strategies and for delivering cognitive remediation. Neuropsychological evaluation pre and post occupational therapy is used to document the result of tailored occupational therapy on cognitive performance. The case studies illustrate the neuropsychological profile of chemothe-rapy-related cognitive changes and the course of deficits over 7-9 months. For younger, educated patients who must return to competitive, fast-paced jobs, cognitive side-effects post-treatment are especially noxious as young adult patients are building their professional lives and are not necessarily provided time to wait for the usual trajectory of recovery to take its course.
Keywords:	adult; human tissue; gene mutation; review; case report; doxorubicin; cancer combination chemotherapy; paclitaxel; cancer radiotherapy; nuclear magnetic resonance imaging; positron emission tomography; multiple cycle treatment; breast cancer; echomammography; mastectomy; lorazepam; cyclophosphamide; cancer survivor; docetaxel; cancer invasion; tumor suppressor gene; insomnia; disease severity; adjuvant chemotherapy; fluorodeoxyglucose f 18; survivorship; neuropsychological test; tamoxifen; adjustment disorder; cognition; cognitive therapy; mixed anxiety and depression; consultation; behavior; cognitive defect; cognitive rehabilitation; daily life activity; occupational therapist; occupational therapy; hot flush; estrogen receptor; progesterone receptor; memory; rehabilitation; genetic screening; intraductal carcinoma; physical performance; breast biopsy; oocyte retrieval; oxycodone; learning; ovary cyst; pregabalin; mini mental state examination; cognitive dysfunction; sensorimotor polyneuropathy; distractibility; hand paresthesia; ovary hyperstimulation
Journal Title:	Psicooncologia
Volume:	8
Issue:	2-3
ISSN:	1696-7240
Publisher:	Universidad Complutense de Madrid
Date Published:	2011-01-01
Start Page:	315
End Page:	342
Language:	English
DOI:	10.5209/rev_PSIC.2011.v8.n2-3.37884
PROVIDER:	scopus
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84855582381&partnerID=40&md5=f35895c88de500ff125dff978d56bde4
Notes:	--- - "Export Date: 1 March 2012" - "Source: Scopus"

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