Nonoperative approach to locally advanced rectal cancer after neoadjuvant combined modality therapy: Challenges and opportunities from a surgical perspective Journal Article


Authors: Fischkoff, K. N.; Ruby, J. A.; Guillem, J. G.
Article Title: Nonoperative approach to locally advanced rectal cancer after neoadjuvant combined modality therapy: Challenges and opportunities from a surgical perspective
Abstract: This review contains a surgical perspective on the evolution of the nonoperative approach to patients with locally advanced rectal cancer who have a clinical complete response after neoadjuvant combined modality therapy, including accuracy of pathologic complete response identification, the timing between neoadjuvant combined modality therapy and assessment of response, the extent of long-term follow-up, and the likelihood of surgical salvage after an initial nonoperative approach. © 2011 Elsevier Inc. All rights reserved.
Keywords: treatment outcome; treatment response; surgical technique; review; advanced cancer; multimodality cancer therapy; cancer adjuvant therapy; combined modality therapy; neoadjuvant therapy; nuclear magnetic resonance imaging; positron emission tomography; follow up; magnetic resonance imaging; computer assisted tomography; surgical approach; patient identification; fluorodeoxyglucose f 18; rectal neoplasms; rectum cancer; transrectal ultrasonography; computed tomography; endorectal ultrasound; fluorodeoxyglucosepositron emission tomography; neoadjuvant combined modality therapy; nonoperative treatment
Journal Title: Clinical Colorectal Cancer
Volume: 10
Issue: 4
ISSN: 1533-0028
Publisher: Elsevier Inc.  
Date Published: 2011-12-01
Start Page: 291
End Page: 297
Language: English
DOI: 10.1016/j.clcc.2011.06.001
PROVIDER: scopus
PUBMED: 21840772
DOI/URL:
Notes: --- - "Export Date: 1 March 2012" - "CODEN: CCCLC" - "Source: Scopus"
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  1. Jose Guillem
    414 Guillem
  2. Jeannine Alberts Ruby
    9 Ruby