Accelerated motion-robust abdominal 3D T1ρ mapping using diamond radial sampling Journal Article

  


Authors: Jogi, S. P.; Peng, Q.; Jafari, R.; Otazo, R.; Wu, C.
Article Title: Accelerated motion-robust abdominal 3D T1ρ mapping using diamond radial sampling
Abstract: <p>Purpose: To develop and validate a fast, motion-robust, free-breathing abdominal 3D T1 rho mapping method by combining variable-density diamond radial k-space sampling with fast-MAPSS (magnetization-prepared angle-modulated partitioned-k-space spoiled gradient-echo snapshots). Methods: 3D MAPSS T1 rho imaging was performed at 3T using five spin-lock time (TSL) pairs in phantom scans and three TSL pairs in nine healthy volunteers. Phantom experiments compared Cartesian sampling (reference) with stack-of-stars and diamond radial sampling. Volunteer scans utilized stack-of-stars and diamond sampling. T1 rho values were calculated using mono-exponential fitting with MAPSS (five or three TSL pairs) and fast-MAPSS (three TSLs). These values were compared across sampling methods and T1 rho techniques in phantom and in vivo for the liver, pancreas, and muscles. Results: Diamond sampling achieved a 2.2-fold acceleration compared to stack-of-stars. In phantom experiments, mean T1 rho differences from reference Cartesian MAPSS were -1.93% for stack-of-stars, and -0.09% for diamond sampling. Fast-MAPSS with three TSLs resulted in differences of 0.54% (stack-of-stars) and 1.45% (diamond). In volunteers, a strong correlation (R-2 >= 0.88) was observed between diamond and stack-of-stars MAPSS, and between MAPSS and fast-MAPSS for both sampling methods. Bland-Altman analysis revealed minimal biases (<1.5 ms) between the methods. Paired t-tests indicated no significant T1 rho differences between MAPSS and fast-MAPSS or between sampling methods in volunteers. Conclusion: Fast-MAPSS with diamond radial k-space sampling enables clinically feasible, motion-robust, free-breathing 3D T1 rho mapping of the abdomen with reduced scan time and quantification accuracy comparable to standard methods.</p>
Keywords: liver; abdomen; biomarker; motion; artifacts; mri; fat; relaxation; radial; t-1-rho; stack-of-stars; t1 rho imaging
Journal Title: Magnetic Resonance in Medicine
ISSN: 0740-3194
Publisher: John Wiley & Sons  
Publication status: Online ahead of print
Date Published: 2025-09-10
Online Publication Date: 2025-09-10
Language: English
ACCESSION: WOS:001569355400001
DOI: 10.1002/mrm.70079
PROVIDER: wos
PUBMED: 40931455
Notes: Source: Wos
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MSK Authors
  1. Jose Ricardo Otazo Torres
    51 Otazo Torres
  2. Can Wu
    23 Wu
  3. Sandeep Panwar Jogi
    2 Jogi
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