Mechanisms guiding the slow pace of maturation in human neurons uncovered Journal Article
| Authors: | Ciceri, G.; Studer, L. |
| Article Title: | Mechanisms guiding the slow pace of maturation in human neurons uncovered |
| Abstract: | Nerve cells in the human brain take a remarkably long time to mature. This study identifies an epigenetic 'barrier' in neural precursor cells that determines the rate of neuronal maturation and is slowly released during the process. Inhibition of the barrier is shown to accelerate maturation in multiple human stem-cell-based models. |
| Keywords: | developmental biology; stem cells; neuroscience |
| Journal Title: | Nature |
| ISSN: | 0028-0836 |
| Publisher: | Nature Publishing Group |
| Publication status: | Online ahead of print |
| Date Published: | 2024-01-01 |
| Online Publication Date: | 2024-01-01 |
| Language: | English |
| ACCESSION: | WOS:001180889000016 |
| DOI: | 10.1038/d41586-023-04141-9 |
| PROVIDER: | wos |
| Notes: | News Item; Early Access -- Source: Wos |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work